Protein-glycosaminoglycan Interactions: Infectiological Aspects

Overview

Journal Med Microbiol Immunol

Specialty Allergy & Immunology

Date 1996 Feb 1

PMID 8811646

Citations 17

Authors

D Sawitzky

Affiliations

Soon will be listed here.

Abstract

Glycosaminoglycans (GAGs) are linear heteropolysaccharides consisting of repeated disaccharide units that are variably N- and O-sulfated. Due to this heterogeneity, GAGs possess a high amount of structural information. Linked to a protein core to form a proteoglycan, GAGs are present on the surface of probably all mammalian tissues. During the recent years, a number of pathogens ranging from viruses to protozoans were found to interact specifically with cell surface GAGs to recognize and bind to their target cells. This review is intended to give a short overview over protein-GAG interaction under the aspects of infection.

Citing Articles

Phosphotransferase System Uptake and Metabolism of the β-Glucoside Salicin Impact Group A Streptococcal Bloodstream Survival and Soft Tissue Infection.

Braza R, Silver A, Sundar G, Davis S, Razi A, Islam E Infect Immun. 2020; 88(10).

PMID: 32719156 PMC: 7504967. DOI: 10.1128/IAI.00346-20.

Streptococcal phosphotransferase system imports unsaturated hyaluronan disaccharide derived from host extracellular matrices.

Oiki S, Nakamichi Y, Maruyama Y, Mikami B, Murata K, Hashimoto W PLoS One. 2019; 14(11):e0224753.

PMID: 31697725 PMC: 6837340. DOI: 10.1371/journal.pone.0224753.

Alternative substrate-bound conformation of bacterial solute-binding protein involved in the import of mammalian host glycosaminoglycans.

Oiki S, Kamochi R, Mikami B, Murata K, Hashimoto W Sci Rep. 2017; 7(1):17005.

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A bacterial ABC transporter enables import of mammalian host glycosaminoglycans.

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Conformational Change in the Active Site of Streptococcal Unsaturated Glucuronyl Hydrolase Through Site-Directed Mutagenesis at Asp-115.

Nakamichi Y, Oiki S, Mikami B, Murata K, Hashimoto W Protein J. 2016; 35(4):300-9.

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References

Kuhn J, Kramer M, Willenbacher W, Wieland U, Lorentzen E, Braun R . Identification of herpes simplex virus type 1 glycoproteins interacting with the cell surface. J Virol. 1990; 64(6):2491-7. PMC: 249424. DOI: 10.1128/JVI.64.6.2491-2497.1990. View

Menozzi F, Gantiez C, Locht C . Interaction of the Bordetella pertussis filamentous hemagglutinin with heparin. FEMS Microbiol Lett. 1991; 78(1):59-64. DOI: 10.1111/j.1574-6968.1991.tb04417.x. View

Sattentau Q, Weiss R . The CD4 antigen: physiological ligand and HIV receptor. Cell. 1988; 52(5):631-3. DOI: 10.1016/0092-8674(88)90397-2. View

Mettenleiter T, Zsak L, Zuckermann F, Sugg N, Kern H, Ben-Porat T . Interaction of glycoprotein gIII with a cellular heparinlike substance mediates adsorption of pseudorabies virus. J Virol. 1990; 64(1):278-86. PMC: 249100. DOI: 10.1128/JVI.64.1.278-286.1990. View

Liang X, Babiuk L, Zamb T . Mapping of heparin-binding structures on bovine herpesvirus 1 and pseudorabies virus gIII glycoproteins. Virology. 1993; 194(1):233-43. DOI: 10.1006/viro.1993.1254. View

Holt G, Pangburn M, Ginsburg V . Properdin binds to sulfatide [Gal(3-SO4)beta 1-1 Cer] and has a sequence homology with other proteins that bind sulfated glycoconjugates. J Biol Chem. 1990; 265(5):2852-5. View

Love D, Esko J, Mosser D . A heparin-binding activity on Leishmania amastigotes which mediates adhesion to cellular proteoglycans. J Cell Biol. 1993; 123(3):759-66. PMC: 2200127. DOI: 10.1083/jcb.123.3.759. View

Nahmias A, KIBRICK S . Inhibitory effect of heparin on herpes simplex virus. J Bacteriol. 1964; 87(5):1060-6. PMC: 277146. DOI: 10.1128/jb.87.5.1060-1066.1964. View

Caughey B . Protease-resistant PrP accumulation and scrapie agent replication: a role for sulphated glycosaminoglycans?. Biochem Soc Trans. 1994; 22(1):163-7. DOI: 10.1042/bst0220163. View

10.

Vaheri A, Cantell K . THE EFFECT OF HEPARIN ON HERPES SIMPLEX VIRUS. Virology. 1963; 21:661-2. DOI: 10.1016/0042-6822(63)90242-3. View

11.

Gerok W, Kottgen E, REUTTER W . Glycoproteins on hepatocytic surfaces. Prog Liver Dis. 1982; 7:87-107. View

12.

Batinic D, Robey F . The V3 region of the envelope glycoprotein of human immunodeficiency virus type 1 binds sulfated polysaccharides and CD4-derived synthetic peptides. J Biol Chem. 1992; 267(10):6664-71. View

13.

Flynn S, Burgett B, Stein D, Wilkinson K, Ryan P . The amino-terminal one-third of pseudorabies virus glycoprotein gIII contains a functional attachment domain, but this domain is not required for the efficient penetration of Vero cells. J Virol. 1993; 67(5):2646-54. PMC: 237586. DOI: 10.1128/JVI.67.5.2646-2654.1993. View

14.

Wyrick P, Choong J, Davis C, Knight S, Royal M, Maslow A . Entry of genital Chlamydia trachomatis into polarized human epithelial cells. Infect Immun. 1989; 57(8):2378-89. PMC: 313458. DOI: 10.1128/iai.57.8.2378-2389.1989. View

15.

Weiss R, Clapham P, Nagy K, Hoshino H . Envelope properties of human T-cell leukemia viruses. Curr Top Microbiol Immunol. 1985; 115:235-46. DOI: 10.1007/978-3-642-70113-9_15. View

16.

Dalgleish A, Beverley P, Clapham P, Crawford D, Greaves M, Weiss R . The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature. 1984; 312(5996):763-7. DOI: 10.1038/312763a0. View

17.

Caughey B, Race R . Potent inhibition of scrapie-associated PrP accumulation by congo red. J Neurochem. 1992; 59(2):768-71. DOI: 10.1111/j.1471-4159.1992.tb09437.x. View

18.

Caughey B, Brown K, Raymond G, Katzenstein G, Thresher W . Binding of the protease-sensitive form of PrP (prion protein) to sulfated glycosaminoglycan and congo red [corrected]. J Virol. 1994; 68(4):2135-41. PMC: 236688. DOI: 10.1128/JVI.68.4.2135-2141.1994. View

19.

Glenner G, Wong C . Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun. 1984; 120(3):885-90. DOI: 10.1016/s0006-291x(84)80190-4. View

20.

Liang O, Ascencio F, Fransson L, Wadstrom T . Binding of heparan sulfate to Staphylococcus aureus. Infect Immun. 1992; 60(3):899-906. PMC: 257571. DOI: 10.1128/iai.60.3.899-906.1992. View