Local Staging of Prostate Carcinoma with Endorectal Coil MRI: Correlation with Whole-mount Radical Prostatectomy Specimens

Overview

Journal Eur Radiol

Specialty Radiology

Date 1996 Jan 1

PMID 8798003

Citations 15

Authors

C Bartolozzi

I Menchi

R Lencioni

S Serni

A Lapini

G Barbanti

A Bozza

A Amorosi

A Manganelli

M Carini

Affiliations

Soon will be listed here.

Abstract

The purpose of this study was to investigate the accuracy of endorectal coil MRI in the local staging of prostate carcinoma. A total of 73 patients with biopsy-proven prostate carcinoma were examined at 0.5 T prior being submitted to radical prostatectomy. The gold standard was provided in all patients by findings at whole-mount sectioning of the surgical specimens. At pathology 28 patients had stage T2, 30 had stage T3a/b, and 15 had stage T3c lesions. Overall accuracy of endorectal coil MRI in defining local tumor stage was 82% (60 of 73 patients). Of 73 patients, 5 (7%) were underestimated and 8 (11%) overestimated. The sensitivity and the specificity of endorectal coil MRI in diagnosing capsular penetration were 95% and 82%, respectively. Seminal vesicle invasion was detected with 80% sensitivity and 93% specificity. Our data indicate that endorectal coil MRI is an accurate method for local staging of prostate cancer.

Citing Articles

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Seminal vesicle invasion in prostate cancer: evaluation by using multiparametric endorectal MR imaging.

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References

Phillips M, Kressel H, Spritzer C, Arger P, Wein A, Marinelli D . Prostatic disorders: MR imaging at 1.5 T. Radiology. 1987; 164(2):386-92. DOI: 10.1148/radiology.164.2.2440074. View

Outwater E, PETERSEN R, Siegelman E, Gomella L, Chernesky C, Mitchell D . Prostate carcinoma: assessment of diagnostic criteria for capsular penetration on endorectal coil MR images. Radiology. 1994; 193(2):333-9. DOI: 10.1148/radiology.193.2.7972739. View

Lee F, Torp-Pedersen S, Littrup P, McLeary R, Mchugh T, Smid A . Hypoechoic lesions of the prostate: clinical relevance of tumor size, digital rectal examination, and prostate-specific antigen. Radiology. 1989; 170(1 Pt 1):29-32. DOI: 10.1148/radiology.170.1.2462262. View

Tempany C, Rahmouni A, Epstein J, Walsh P, Zerhouni E . Invasion of the neurovascular bundle by prostate cancer: evaluation with MR imaging. Radiology. 1991; 181(1):107-12. DOI: 10.1148/radiology.181.1.1887017. View

Pontes J, Eisenkraft S, Watanabe H, Ohe H, Saitoh M, Murphy G . Preoperative evaluation of localized prostatic carcinoma by transrectal ultrasonography. J Urol. 1985; 134(2):289-91. DOI: 10.1016/s0022-5347(17)47127-8. View

SCHNALL M, Imai Y, Tomaszewski J, POLLACK H, Lenkinski R, Kressel H . Prostate cancer: local staging with endorectal surface coil MR imaging. Radiology. 1991; 178(3):797-802. DOI: 10.1148/radiology.178.3.1994421. View

Engeler C, Wasserman N, Zhang G . Preoperative assessment of prostatic carcinoma by computerized tomography. Weaknesses and new perspectives. Urology. 1992; 40(4):346-50. DOI: 10.1016/0090-4295(92)90386-b. View

Voges G, McNeal J, Redwine E, Freiha F, Stamey T . Morphologic analysis of surgical margins with positive findings in prostatectomy for adenocarcinoma of the prostate. Cancer. 1992; 69(2):520-6. DOI: 10.1002/1097-0142(19920115)69:2<520::aid-cncr2820690240>3.0.co;2-v. View

Middleton R, Smith Jr J, MELZER R, Hamilton P . Patient survival and local recurrence rate following radical prostatectomy for prostatic carcinoma. J Urol. 1986; 136(2):422-4. DOI: 10.1016/s0022-5347(17)44890-7. View

10.

Ohori M, Scardino P, Lapin S, Link J, Wheeler T . The mechanisms and prognostic significance of seminal vesicle involvement by prostate cancer. Am J Surg Pathol. 1993; 17(12):1252-61. DOI: 10.1097/00000478-199312000-00006. View

11.

Stamey T, Freiha F, McNeal J, Redwine E, Whittemore A, Schmid H . Localized prostate cancer. Relationship of tumor volume to clinical significance for treatment of prostate cancer. Cancer. 1993; 71(3 Suppl):933-8. DOI: 10.1002/1097-0142(19930201)71:3+<933::aid-cncr2820711408>3.0.co;2-l. View

12.

Schiebler M, SCHNALL M, POLLACK H, Lenkinski R, Tomaszewski J, Wein A . Current role of MR imaging in the staging of adenocarcinoma of the prostate. Radiology. 1993; 189(2):339-52. DOI: 10.1148/radiology.189.2.8210358. View

13.

Walsh P, Lepor H . The role of radical prostatectomy in the management of prostatic cancer. Cancer. 1987; 60(3 Suppl):526-37. DOI: 10.1002/1097-0142(19870801)60:3+<526::aid-cncr2820601515>3.0.co;2-9. View

14.

Martin J, Hajek P, Baker L, Mattrey R . Inflatable surface coil for MR imaging of the prostate. Radiology. 1988; 167(1):268-70. DOI: 10.1148/radiology.167.1.3347731. View

15.

Mirowitz S, Brown J, Heiken J . Evaluation of the prostate and prostatic carcinoma with gadolinium-enhanced endorectal coil MR imaging. Radiology. 1993; 186(1):153-7. DOI: 10.1148/radiology.186.1.8416557. View

16.

SCHNALL M, Lenkinski R, POLLACK H, Imai Y, Kressel H . Prostate: MR imaging with an endorectal surface coil. Radiology. 1989; 172(2):570-4. DOI: 10.1148/radiology.172.2.2748842. View

17.

Tempany C, Zhou X, Zerhouni E, Rifkin M, Quint L, Piccoli C . Staging of prostate cancer: results of Radiology Diagnostic Oncology Group project comparison of three MR imaging techniques. Radiology. 1994; 192(1):47-54. DOI: 10.1148/radiology.192.1.8208963. View

18.

Salo J, Kivisaari L, Rannikko S, Lehtonen T . Computerized tomography and transrectal ultrasound in the assessment of local extension of prostatic cancer before radical retropubic prostatectomy. J Urol. 1987; 137(3):435-8. DOI: 10.1016/s0022-5347(17)44059-6. View

19.

Heiken J, Forman H, Brown J . Neoplasms of the bladder, prostate, and testis. Radiol Clin North Am. 1994; 32(1):81-98. View

20.

SCHNALL M, Bezzi M, POLLACK H, Kressel H . Magnetic resonance imaging of the prostate. Magn Reson Q. 1990; 6(1):1-16. View