Characterisation of Vha26, the Drosophila Gene for a 26 KDa E-subunit of the Vacuolar ATPase
Overview
Biophysics
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A Drosophila melanogaster gene and cDNA for the E-subunit of the V-ATPase were characterised. The deduced product has 226 amino acids and a molecular mass of 26.1 kDa. The gene is a single copy at 83B1-4 on chromosome 3R. The coding sequence is punctuated by three introns which do not align with those in Neurospora. The gene is ubiquitously expressed as an mRNA of 2.3 kb. but at lower levels in pupae.
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