Isolation and Characterization of the First Simian Immunodeficiency Virus from a Feral Sooty Mangabey (Cercocebus Atys) in West Africa

Overview

Journal J Med Primatol

Publisher Wiley

Date 1995 May 1

PMID 8751049

Citations 19

Authors

Z Chen

P Telfer

P Reed

L Zhang

A Getti

D D Ho

P A Marx

Affiliations

Soon will be listed here.

Abstract

The lineage of HIV-2-like viruses was studied in feral sooty mangabeys (SMs) by serological and genetic methods. Four feral sooty mangabeys were positive for simian immunodeficiency virus (SIV) antibodies and a new isolate, SIVsmSL92a, was obtained. Genetic analysis of gag genes showed that SIVsmSL92a was highly diverse and a distinct sequence subtype within the SIV sm/HIV-2 family. The results showed that SIVsm is the most diverse group of SIVs found thus far in a single monkey species.

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