Circulating Immune Complexes in Intracranial Neoplasms
Overview
Overview
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
The levels of circulating immune complexes (CIC) were assayed in the sera of 109 patients with intracranial space occupying lesions. The CIC levels were significantly increased in all the brain tumours. After treatment, the CIC levels were still significantly increased when compared to the controls but showed no change when compared to their respective pre-operative values. Further, no change was observed in the CIC levels between the malignant and benign tumour case. Moreover, in brain tumours, 90% of the CIC precipitate consisted of IgG. However, the CIC levels fail to prognosticate the process of the disease in these patients.
References
1.
Rossen R, Reisberg M, Hersh E, Gutterman J
. The C1q binding test for soluble immune complexes: clinical correlations obtained in patients with cancer. J Natl Cancer Inst. 1977; 58(5):1205-15.
DOI: 10.1093/jnci/58.5.1205.
View
2.
SILVER H, Karim K, Archibald E, Salinas F
. Serum sialic acid and sialyltransferase as monitors of tumor burden in malignant melanoma patients. Cancer Res. 1979; 39(12):5036-42.
View
3.
Fust G, Fekete B, Angyal I, Jakab A, Pal A, Meretey K
. Evaluation of different methods for detecting circulating immune complexes. Studies in patients with lung cancer. J Immunol Methods. 1981; 46(3):259-76.
DOI: 10.1016/0022-1759(81)90311-2.
View
4.
Vlock D
. Immunobiologic aspects of head and neck cancer. Clinical and laboratory correlates. Hematol Oncol Clin North Am. 1991; 5(4):797-820.
View
5.
Theofilopoulos A, Dixon F
. The biology and detection of immune complexes. Adv Immunol. 1979; 28:89-220.
DOI: 10.1016/s0065-2776(08)60800-7.
View