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Acetylator Phenotype in Diabetic Neuropathy

Overview
Journal Br Med J
Specialty General Medicine
Date 1977 Jul 30
PMID 871863
Citations 17
Authors
E H McLaren
A C Burden
P J Moorhead
Affiliations
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Abstract

The proportions of slow and fast acetylators in a group of diabetics with symptomatic peripheral neuropathy were compared with those in a group of diabetics who had had the disease for at least 10 years without developing neuropathy. There was a significantly higher proportion of fast acetylators in the group of diabetics without neuropathy than in those with neuropathy or in the normal population. Hence genetic factors separate from the diabetic diathesis may determine the development of neuropathy in any particular diabetic.

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