Fluctuations of Serum and Bile Lipid Concentrations During the Menstrual Cycle

Overview

Journal Br Med J

Specialty General Medicine

Date 1977 Jun 18

PMID 871668

Citations 11

Authors

A C Wicks

K W Heaton

P Durrington

J Yeates

Affiliations

Soon will be listed here.

Abstract

We measured fasting serum and bile lipid concentrations at three intervals during the normal menstrual cycles of 11 healthy women not taking oral contraceptives. In nine of them cholesterol saturation of bile, and therefore presumably the risk of developing gall stones, was higher nine days after midcycle than at the end of menstruation. This change in bile cholesterol saturation was preceded by a significant fall in serum lipid concentrations: during the nine days after mid-cycle serum triglyceride and cholesterol concentrations fell in nine and eight of the 11 women respectively. Changes in the composition of serum and biliary lipids during the menstrual cycle are presumably due to a direct effect of sex hormones on the liver.

Citing Articles

Effects of fasting on the composition of gallbladder bile.

Bloch H, Thornton J, Heaton K Gut. 1980; 21(12):1087-9.

PMID: 7461468 PMC: 1419405. DOI: 10.1136/gut.21.12.1087.

Biliary lipids, bile acids, and gallbladder function in the human female. Effects of pregnancy and the ovulatory cycle.

KERN Jr F, Everson G, DeMark B, McKinley C, Showalter R, Erfling W J Clin Invest. 1981; 68(5):1229-42.

PMID: 7298849 PMC: 370918. DOI: 10.1172/JCI110369.

Fluctuations of serum bile acid concentrations during the menstrual cycle.

Pennington C, Ross P, Murison J, Bouchier I J Clin Pathol. 1981; 34(2):185-6.

PMID: 7229099 PMC: 1146449. DOI: 10.1136/jcp.34.2.185.

Effect of menstrual stress on serum lipid levels.

Choksi S, Sane A Experientia. 1981; 37(1):58-9.

PMID: 7193600 DOI: 10.1007/BF01965567.

Effect of female sex hormones on lithogenicity of bile.

Nakagaki M, Nakayama F Jpn J Surg. 1982; 12(1):13-8.

PMID: 7069944 DOI: 10.1007/BF02469009.

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