Sequencing and Functional Analysis of the Genome of Bacillus Subtilis Strain 168

Overview

Journal FEBS Lett

Specialty Biochemistry

Date 1996 Jun 24

PMID 8682212

Citations 27

Authors

C R Harwood

A Wipat

Affiliations

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Abstract

The international programme to sequence the 4.2 Mb genome of Bacillus subtilis, a model Gram-positive bacterium, is a joint project involving European, Japanese and US research groups. To date ca. 3.0 Mb of the genome has been sequenced, with the remaining 1.2 Mb expected to be completed in 1997. The amenability of B.subtilis to genetic manipulation, combined with the availability of extensive expertise on its biochemistry and physiology, makes this bacterium a valuable organism in which to investigate the properties of genes for which functions cannot be readily ascribed by standard methods.

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