» Articles » PMID: 8674382

Gastrointestinal Symptoms and Psychiatric Disorders in the General Population. Findings from NIMH Epidemiologic Catchment Area Project

Overview
Journal Dig Dis Sci
Specialty Gastroenterology
Date 1996 Apr 1
PMID 8674382
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

High rates of psychiatric disorder have been documented in patients with functional bowel syndromes sampled from physicians' offices. Lifetime psychiatric disorder and/or current psychiatric symptoms are thought to be much more highly associated with current gastrointestinal bowel symptoms in clinical settings than in the community. The relationship of lifetime functional gastrointestinal symptoms to lifetime psychiatric disorders has not been examined systematically in randomly selected samples of general community populations. The current study reports findings from existing data on a large, randomly selected population sample that may help to clarify these associations. Epidemiologic Catchment Area (ECA) project data were analyzed to examine relationships of functional gastrointestinal symptoms and psychiatric diagnoses in the community. Individuals with two or more medically unexplained gastrointestinal symptoms had high rates of psychiatric disorders. This was also true for the subgroup in which abdominal pain was one of the two symptoms. The overwhelming majority of subjects reporting medically unexplained gastrointestinal symptoms said they had consulted physicians for those symptoms. General population ECA data indicate that women in the community report more functional gastrointestinal complaints than men, that individuals with lifetime gastrointestinal complaints have high rates of lifetime psychiatric disorders (not necessarily currently symptomatic), and most have contacted a physician regarding their gastrointestinal symptoms. These data complement studies showing that patients with current gastrointestinal symptoms often do not consult a physician, or when they do, such behavior is associated with active psychiatric symptoms. These present data are consistent with the hypothesis that patients with recurrent symptoms are those who routinely seek medical help and who have high rates of psychiatric disorders, whereas those with symptoms that resolve or are improved by a medical intervention do not maintain treatment-seeking behavior.

Citing Articles

Gastric symptoms and low perceived maternal warmth are associated with eating disorder symptoms in young adolescent girls.

Kerr K, Ralph-Nearman C, Colaizzi J, DeVille D, Breslin F, Aupperle R Int J Eat Disord. 2021; 54(6):1009-1018.

PMID: 33836108 PMC: 9945938. DOI: 10.1002/eat.23516.


Relationship of functional gastrointestinal disorders and psychiatric disorders: implications for treatment.

North C, Hong B, Alpers D World J Gastroenterol. 2007; 13(14):2020-7.

PMID: 17465442 PMC: 4319119. DOI: 10.3748/wjg.v13.i14.2020.


CRF1 receptor signaling pathways are involved in stress-related alterations of colonic function and viscerosensitivity: implications for irritable bowel syndrome.

Tache Y, Martinez V, Wang L, Million M Br J Pharmacol. 2004; 141(8):1321-30.

PMID: 15100165 PMC: 1574904. DOI: 10.1038/sj.bjp.0705760.


Psychologic Therapies for Irritable Bowel Syndrome.

Boyce P Curr Treat Options Gastroenterol. 2001; 4(4):323-331.

PMID: 11469991 DOI: 10.1007/s11938-001-0058-7.


Fundamentals of neurogastroenterology.

Wood J, Alpers D, Andrews P Gut. 1999; 45 Suppl 2:II6-II16.

PMID: 10457039 PMC: 1766686. DOI: 10.1136/gut.45.2008.ii6.


References
1.
Heaton K, ODonnell L, Braddon F, Mountford R, Hughes A, Cripps P . Symptoms of irritable bowel syndrome in a British urban community: consulters and nonconsulters. Gastroenterology. 1992; 102(6):1962-7. DOI: 10.1016/0016-5085(92)90320-x. View

2.
Fava G, Pavan L . Large bowel disorders. II. Psychopathology and alexithymia. Psychother Psychosom. 1976; 27(2):100-5. DOI: 10.1159/000287003. View

3.
Walker E, Katon W, Jemelka R . Comorbidity of gastrointestinal complaints, depression, and anxiety in the Epidemiologic Catchment Area (ECA) Study. Am J Med. 1992; 92(1A):26S-30S. DOI: 10.1016/0002-9343(92)90133-v. View

4.
Regier D, MYERS J, Kramer M, ROBINS L, Blazer D, Hough R . The NIMH Epidemiologic Catchment Area program. Historical context, major objectives, and study population characteristics. Arch Gen Psychiatry. 1984; 41(10):934-41. DOI: 10.1001/archpsyc.1984.01790210016003. View

5.
Goldberg D, Steele J, Johnson A, Smith C . Ability of primary care physicians to make accurate ratings of psychiatric symptoms. Arch Gen Psychiatry. 1982; 39(7):829-33. DOI: 10.1001/archpsyc.1982.04290070059011. View