Heterotopic Pancreas. A Difficult Diagnosis

Overview

Journal Dig Dis Sci

Specialty Gastroenterology

Date 1996 Jun 1

PMID 8654158

Citations 10

Authors

S P Monig

M Selzner

M Raab

S Eidt

Affiliations

Soon will be listed here.

Abstract

Heterotopic pancreas is seen in one of every 500 laparotomies or 0.55-13% of autopsies. Despite modern diagnostic procedures (endoscopy, endoscopic ultrasound) it is difficult to diagnose preoperatively. A 51-year-old patient with a 30-year history of recurrent gastric ulcers was diagnosed with a gastric wall tumor. Endoscopic biopsy sample showed normal gastric mucosa. Endoscopic ultrasound and contrast radiography were not able to specify the gastric wall tumor. The local excision and histologic preparation of the tumor showed heterotopic pancreatic tissue within the gastric submucosa without any signs of malignancy. Three years postoperatively the patient is without any complaints. There have been no further signs of gastric ulcers.

Citing Articles

Clinical classification of symptomatic heterotopic pancreas of the stomach and duodenum: A case series and systematic literature review.

LeCompte M, Mason B, Robbins K, Yano M, Chatterjee D, Fields R World J Gastroenterol. 2022; 28(14):1455-1478.

PMID: 35582670 PMC: 9048474. DOI: 10.3748/wjg.v28.i14.1455.

Submucosal Tunneling Endoscopic Resection for the Management of Heterotopic Pancreas With Cystic Degeneration.

Almazan E, Runge T, Li Q, Ngamruengphong S ACG Case Rep J. 2020; 7(7):e00419.

PMID: 32766361 PMC: 7357709. DOI: 10.14309/crj.0000000000000419.

Pancreatic intraepithelial neoplasia in heterotopic pancreas: incidentally diagnosed on endoscopic mucosal resection of a duodenal polyp.

Safadi S, Martin D, Rustagi T BMJ Case Rep. 2018; 2018.

PMID: 29936443 PMC: 6020903. DOI: 10.1136/bcr-2018-224414.

Heterotopic pancreas causing duodenal obstruction in a patient previously treated for choledochal cyst.

Deshpande V, Raghunath B, Sarin Y, Sinha S J Indian Assoc Pediatr Surg. 2012; 17(1):40-2.

PMID: 22279366 PMC: 3263040. DOI: 10.4103/0971-9261.91088.

Premalignant gastric heterotopic pancreas.

Sadeghi N, Godambe A, Shienbaum A, Alloy A Gastroenterol Hepatol (N Y). 2011; 4(3):218-21.

PMID: 21904502 PMC: 3088303.

References

Nelson R, SCOTT Jr N . Heterotopic pancreatic tissue in the stomach; gastroscopic features. Gastroenterology. 1958; 34(3):452-9. View

Carr M, Deiraniya A, Judd P . Mediastinal cyst containing mural pancreatic tissue. Thorax. 1977; 32(4):512-6. PMC: 470664. DOI: 10.1136/thx.32.4.512. View

Qizilbash A . Acute pancreatitis occurring in heterotopic pancreatic tissue in the gallbladder. Can J Surg. 1976; 19(5):413-4. View

Barrocas A, Fontenelle L, WILLIAMS M . Gastric heterotopic pancreas: a case report and review of literature. Am Surg. 1973; 39(6):361-5. View

Flejou J, POTET F, Molas G, Bernades P, Amouyal P, Fekete F . Cystic dystrophy of the gastric and duodenal wall developing in heterotopic pancreas: an unrecognised entity. Gut. 1993; 34(3):343-7. PMC: 1374138. DOI: 10.1136/gut.34.3.343. View

De Friend D, Humphrey C, Foster D . Symptomatic pancreatic heterotopia treated by local excision. Gut. 1991; 32(3):332-3. PMC: 1378847. DOI: 10.1136/gut.32.3.332. View

HUDOCK J, Wanner H, REILLY C . Acute massive gastro-intestinal hemorrhage associated with pancreatic heterotopic tissue of the stomach. Ann Surg. 1956; 143(1):121-5. PMC: 1464949. DOI: 10.1097/00000658-195601000-00017. View

DE CASTRO BARBOSA J, DOCKERTY M, WAUGH J . Pancreatic heterotopia; review of the literature and report of 41 authenticated surgical cases, of which 25 were clinically significant. Surg Gynecol Obstet. 2010; 82:527-42. View

Murayama H, Kikuchi M, Imai T, Yamamoto Y, Iwata Y . A case of heterotopic pancreas in lymph node. Virchows Arch A Pathol Anat Histol. 1978; 377(2):175-9. DOI: 10.1007/BF00427004. View

10.

Mason T, Quagliarello J . Ectopic pancreas in the fallopian tube. Report of a first case. Obstet Gynecol. 1976; 48(1 Suppl):70S-75S. View

11.

Nopajaroonsri C . Mucus retention in heterotopic pancreas of the gastric antrum. A lesion mimicking mucinous carcinoma. Am J Surg Pathol. 1994; 18(9):953-7. DOI: 10.1097/00000478-199409000-00011. View

12.

Razi M . Ectopic pancreatic tissue of esophagus with massive upper gastrointestinal bleeding. Arch Surg. 1966; 92(1):101-4. DOI: 10.1001/archsurg.1966.01320190103024. View

13.

Clark R, Teplick S . Ectopic pancreas causing massive upper gastrointestinal hemorrhage. Report of a case diagnosed arteriographically. Gastroenterology. 1975; 69(6):1331-3. View

14.

Tanaka K, Tsunoda T, Eto T, Yamada M, Tajima Y, Shimogama H . Diagnosis and management of heterotopic pancreas. Int Surg. 1993; 78(1):32-5. View

15.

Kaneda M, Yano T, Yamamoto T, Suzuki T, Fujimori K, Itoh H . Ectopic pancreas in the stomach presenting as an inflammatory abdominal mass. Am J Gastroenterol. 1989; 84(6):663-6. View

16.

Rose C, Kessaram R, LIND J . Ectopic gastric pancreas: a review and report of 4 cases. Diagn Imaging. 1980; 49(4):214-8. View