Is the Renal Vasodilatation Induced by Beta-adrenoceptor Stimulants in the Dog Mediated Through Dopamine Receptor?

Overview

Journal Experientia

Specialty Science

Date 1977 May 15

PMID 862800

Citations 3

Authors

C Bell

M K Mya

Affiliations

Soon will be listed here.

Abstract

In chloralose-anaesthetized dogs the renal vasodilator effect of isoprenaline is depressed by blockade of either dopamine or beta-adrenoceptors but the renal vasodilator effect of dopamine is depressed only by blockade of dopamine receptors. This suggests that the vasodilatation induced by beta-stimulants within the canine kidney is due in part to activation of dopamine receptors.

Citing Articles

Effect of isoprenaline on dopamine receptors in the rabbit isolated renal artery.

Kelly M Experientia. 1981; 37(8):889-90.

PMID: 6269874 DOI: 10.1007/BF01985697.

Localization of vasodilator dopamine receptors in the canine hindlimb.

Bell C, Stubbs A Br J Pharmacol. 1978; 64(2):253-7.

PMID: 708994 PMC: 1668307. DOI: 10.1111/j.1476-5381.1978.tb17297.x.

Evidence for dopaminergic vasodilator innervation of the canine paw pad.

Bell C, Lang W Br J Pharmacol. 1979; 67(3):337-43.

PMID: 40651 PMC: 2044003. DOI: 10.1111/j.1476-5381.1979.tb08685.x.

References

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Yeh B, MCNAY J, Goldberg L . Attenuation of dopamine renal and mesenteric vasodilation by haloperidol: evidence for a specific dopamine receptor. J Pharmacol Exp Ther. 1969; 168(2):303-9. View

Bell C, Conway E, Lang W, PADANYI R . Vascular dopamine receptors in the canine hindlimb. Br J Pharmacol. 1975; 55(2):167-72. PMC: 1666846. DOI: 10.1111/j.1476-5381.1975.tb07625.x. View

Chokshi D, Yeh B, SAMET P . Effects of dopamine and isoproterenol on renin secretion in the dog. Proc Soc Exp Biol Med. 1972; 140(1):54-7. DOI: 10.3181/00379727-140-36394. View

Toda N, Goldberg L . Effects of dopamine on isolated canine coronary arteries. Cardiovasc Res. 1975; 9(3):384-89. DOI: 10.1093/cvr/9.3.384. View