Histological Changes in the Liver and Indices of Drug Metabolism in Alcoholics

Overview

Journal Eur J Clin Pharmacol

Specialty Pharmacology

Date 1977 Apr 20

PMID 862651

Citations 34

Authors

E A Sotaniemi

J Ahlqvist

R O Pelkonen

H Pirttiaho

P V Luoma

Affiliations

Soon will be listed here.

Citing Articles

Serum selenium, glutathione peroxidase, lipids, and human liver microsomal enzyme activity : A double-blind controlled trial of selenium supplementation.

Luoma P, Korpela H, Sotaniemi E, Kumpulainen J Biol Trace Elem Res. 2013; 8(2):113-21.

PMID: 24257871 DOI: 10.1007/BF02917465.

The pharmacokinetics of Casodex enantiomers in subjects with impaired liver function.

Cockshott I, Sotaniemi E, Cooper K, Jones D Br J Clin Pharmacol. 1993; 36(4):339-43.

PMID: 12959312 PMC: 1364687. DOI: 10.1111/j.1365-2125.1993.tb00373.x.

CYP3A4 and CYP2A6 activities marked by the metabolism of lignocaine and coumarin in patients with liver and kidney diseases and epileptic patients.

Sotaniemi E, Rautio A, Backstrom M, Arvela P, Pelkonen O Br J Clin Pharmacol. 1995; 39(1):71-6.

PMID: 7756103 PMC: 1364984. DOI: 10.1111/j.1365-2125.1995.tb04412.x.

Serum sex hormone levels after replacing carbamazepine with oxcarbazepine.

Isojarvi J, Pakarinen A, Rautio A, Pelkonen O, Myllyla V Eur J Clin Pharmacol. 1995; 47(5):461-4.

PMID: 7720770 DOI: 10.1007/BF00196862.

Drug metabolism and liver function after methyldopa withdrawal.

Ylikallio A, Sotaniemi E Br J Clin Pharmacol. 1980; 10(2):115-9.

PMID: 7426273 PMC: 1430037. DOI: 10.1111/j.1365-2125.1980.tb01727.x.

References

Sotaniemi E, Kontturi M, LARMI T . Drug metabolism and androgen control therapy in prostatic cancer. Clin Pharmacol Ther. 1973; 14(3):413-7. DOI: 10.1002/cpt1973143413. View

Vesell E, Page J, PASSANANTI G . Genetic and environmental factors affecting ethanol metabolism in man. Clin Pharmacol Ther. 1971; 12(2):192-201. DOI: 10.1002/cpt1971122part1192. View

Rubin E, Gang H, Misra P, Lieber C . Inhibition of drug metabolism by acute ethanol intoxication. A hepatic microsomal mechanism. Am J Med. 1970; 49(6):801-6. DOI: 10.1016/s0002-9343(70)80061-4. View

Lieber C, DECARLI L . Ethanol oxidation by hepatic microsomes: adaptive increase after ethanol feeding. Science. 1968; 162(3856):917-8. DOI: 10.1126/science.162.3856.917. View

Seligson D, Marino J, Dodson E . Determination of sulfobromophthalein in serum. Clin Chem. 1957; 3(5):638-45. View

Omura T, Sato R . THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE. J Biol Chem. 1964; 239:2370-8. View

Rubin E, HUTTERER F, Lieber C . Ethanol increases hepatic smooth endoplasmic reticulum and drug-metabolizing enzymes. Science. 1968; 159(3822):1469-70. DOI: 10.1126/science.159.3822.1469. View

Cohn J, Khatri I, Groszmann R, Kotelanski B . Hepatic blood flow in alcoholic liver disease measured by an indicator dilution technic. Am J Med. 1972; 53(6):704-14. DOI: 10.1016/0002-9343(72)90187-8. View

Thomson P, Melmon K, Richardson J, Cohn K, Steinbrunn W, Cudihee R . Lidocaine pharmacokinetics in advanced heart failure, liver disease, and renal failure in humans. Ann Intern Med. 1973; 78(4):499-508. DOI: 10.7326/0003-4819-78-4-499. View

10.

Nelson E . RATE OF METABOLISM OF TOLBUTAMIDE IN TEST SUBJECTS WITH LIVER DISEASE OR WITH IMPAIRED RENAL FUNCTION. Am J Med Sci. 1964; 248:657-9. DOI: 10.1097/00000441-196412000-00004. View

11.

Branch R, Herbert C, Read A . Determinants of serum antipyrine half-lives in patients with liver disease. Gut. 1973; 14(7):569-73. PMC: 1412804. DOI: 10.1136/gut.14.7.569. View

12.

Wilkinson G, SHAND D . Commentary: a physiological approach to hepatic drug clearance. Clin Pharmacol Ther. 1975; 18(4):377-90. DOI: 10.1002/cpt1975184377. View

13.

Ahlqvist J . Liver mast cell counts during development of cirrhosis of the liver in rats on a low protein, high fat diet. Acta Pathol Microbiol Scand Suppl. 1960; 50(Suppl 142):1-64. View

14.

Mawer G, MILLER N, Turnberg L . Metabolism of amylobarbitone in patients with chronic liver disease. Br J Pharmacol. 1972; 44(3):549-60. PMC: 1665818. DOI: 10.1111/j.1476-5381.1972.tb07292.x. View

15.

Ahlqvist J . Transverse mounting of ribbons on groups of slides for comparing different stains in adjacent sections. Stain Technol. 1970; 45(1):38-9. View

16.

Rubin E, Lieber C . Hepatic microsomal enzymes in man and rat: induction and inhibition by ethanol. Science. 1968; 162(3854):690-1. DOI: 10.1126/science.162.3854.690. View

17.

Shah M, Clancy B, Iber F . Comparison of blood clearance of ethanol and tolbutamide and the activity of hepatic ethanol-oxidizing and drug-metabolizing enzymes in chronic alcoholic subjects. Am J Clin Nutr. 1972; 25(2):135-9. DOI: 10.1093/ajcn/25.2.135. View

18.

Klotz U, McHorse T, Wilkinson G, Schenker S . The effect of cirrhosis on the disposition and elimination of meperidine in man. Clin Pharmacol Ther. 1974; 16(4):667-75. DOI: 10.1002/cpt1974164667. View

19.

Kater R, Roggin G, Tobon F, Zieve P, Iber F . Increased rate of clearance of drugs from the circulation of alcoholics. Am J Med Sci. 1969; 258(1):35-9. DOI: 10.1097/00000441-196907000-00005. View

20.

Klotz U, Avant G, Hoyumpa A, Schenker S, Wilkinson G . The effects of age and liver disease on the disposition and elimination of diazepam in adult man. J Clin Invest. 1975; 55(2):347-59. PMC: 301753. DOI: 10.1172/JCI107938. View