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Continuous Epidural Morphine/butorphanol Infusion Following Selective Dorsal Rhizotomy in Children

Overview
Specialty Pediatrics
Date 1995 Nov 1
PMID 8608576
Citations 2
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Abstract

The authors prospectively evaluated 15 patients who had undergone selective dorsal rhizotomy who were given a continuous morphine/butorphanol infusion, to determine whether variations in the postoperative pain control and side effects seen using a bolus technique could be reduced. Patients had an epidural catheter placed at the end of the operative procedure through which 50-60 micrograms/kg preservative-free morphine and 15-20 micrograms/kg butorphanol was administered. A continuous epidural infusion of 5 micrograms/kg h morphine and 1.2 micrograms/kg h butorphanol was then initiated. Postoperatively, mean pain scores were excellent. No patient required additional systemic analgesics during the 72-h investigational period. A low incidence of nausea, and no vomiting, pruritus, or respiratory depression was reported by the cohort. All patients maintained oxygen saturations above 95%. This indicates that the use of a continuous epidural infusion provides excellent pain control, decreases the occurrence of untoward side effects, and allows the early initiation of occupational and physical therapy postoperatively.

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References
1.
Grass J . Fentanyl: clinical use as postoperative analgesic--epidural/intrathecal route. J Pain Symptom Manage. 1992; 7(7):419-30. DOI: 10.1016/0885-3924(92)90022-a. View

2.
Lawhorn C, Boop F, Brown R, Andelman P . Epidural pain management in the postrhizotomy patient. Pediatr Neurosurg. 1994; 20(3):198-202. DOI: 10.1159/000120788. View

3.
Dalens B, Tanguy A, Haberer J . Lumbar epidural anesthesia for operative and postoperative pain relief in infants and young children. Anesth Analg. 1986; 65(10):1069-73. View

4.
Lawhorn C, McNitt J, Fibuch E, Joyce J, Leadley Jr R . Epidural morphine with butorphanol for postoperative analgesia after cesarean delivery. Anesth Analg. 1991; 72(1):53-7. DOI: 10.1213/00000539-199101000-00009. View

5.
Boop F, CHADDUCK W . Selective posterior rhizotomy for relief of spasticity. J Ark Med Soc. 1991; 87(12):512-4. View