Progress with the PRINTS Protein Fingerprint Database

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 1996 Jan 1

PMID 8594576

Citations 5

Authors

T K Attwood

M E BECK

A J Bleasby

K Degtyarenko

D J Parry Smith

Affiliations

Soon will be listed here.

Abstract

PRINTS is a compendium of protein motif 'fingerprints' derived from the OWL composite sequence database. Fingerprints are groups of motifs within sequence alignments whose conserved nature allows them to be used as signatures of family membership. To date, 400 fingerprints have been constructed and stored in Prints, the size of which has doubled in the last year. The current version, 9.0, encodes approximately 2000 motifs, covering a range of globular and membrane proteins, modular polypeptides, and so on. Fingerprints inherently offer improved diagnostic reliability over single motif methods by virtue of the mutual context provided by motif neighbours. PRINTS thus provides a useful adjunct to the widely used PROSITE dictionary of patterns. The database is now accessible via the Database Browser on the UCL Bioinformatics server at http://www.biochem.ucl.ac.uk/bsm/dbbrowser .

Citing Articles

Compilation and analysis of intein sequences.

Perler F, Olsen G, Adam E Nucleic Acids Res. 1997; 25(6):1087-93.

PMID: 9092614 PMC: 146560. DOI: 10.1093/nar/25.6.1087.

The directory of P450-containing systems in 1996.

Fabian P, Degtyarenko K Nucleic Acids Res. 1997; 25(1):274-7.

PMID: 9016553 PMC: 146390. DOI: 10.1093/nar/25.1.274.

The SBASE protein domain library, release 5.0: a collection of annotated protein sequence segments.

Fabian P, Murvai J, Hatsagi Z, Vlahovicek K, Hegyi H, Pongor S Nucleic Acids Res. 1997; 25(1):240-3.

PMID: 9016545 PMC: 146372. DOI: 10.1093/nar/25.1.240.

Novel developments with the PRINTS protein fingerprint database.

Attwood T, BECK M, Bleasby A, Degtyarenko K, Michie A, Parry-Smith D Nucleic Acids Res. 1997; 25(1):212-7.

PMID: 9016538 PMC: 146411. DOI: 10.1093/nar/25.1.212.

The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae.

Terbush D, Maurice T, Roth D, Novick P EMBO J. 1996; 15(23):6483-94.

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