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The African Swine Fever Virus IAP Homolog is a Late Structural Polypeptide

Overview
Journal Virology
Specialty Microbiology
Date 1995 Dec 20
PMID 8553574
Citations 24
Authors
M R Chacon
F Almazan
M L Nogal
E Vinuela
J F Rodriguez
Affiliations
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Abstract

The analysis of the complete nucleotide sequence of the African swine fever virus genome has revealed the existence of a number of genes potentially capable of modifying the host's response to the virus infection. In this report, we describe the results of the characterization of the A224L gene that encodes a novel member of the family of apoptosis inhibitors known as IAP proteins. A224L is expressed during the late phase of the infectious cycle, and its polypeptide product is assembled into virus particles.

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