Serological Cross-reactions Between Moraxella (Branhamella) Catarrhalis and Other Oropharyngeal Bacteria

Overview

Journal Eur J Clin Microbiol Infect Dis

Publisher Springer

Specialties Infectious Diseases
Microbiology

Date 1993 Apr 1

PMID 8513818

Citations 4

Authors

I Jonsson

T Holme

A Krook

M Thoren

Affiliations

Soon will be listed here.

Abstract

Oropharyngeal bacteria belonging to different species were tested for serological cross-reactions with Moraxella catarrhalis using sera from immunized rabbits. Sera were tested using immunofluorescence, an enzyme immunoassay (EIA) and immunoblotting. On immunofluorescence, significant cross-reactions were demonstrated with beta-hemolytic streptococci group A and group G, as well as with streptococci of the viridans group. Some cross-reactions were also noted with Neisseria meningitidis. In the EIA, strong cross-reactions were demonstrated with beta-hemolytic streptococci. No cross-reactions were obtained with Streptococcus pneumoniae, Haemophilus influenzae or common oral Neisseria. The results are of importance for the interpretation of serological tests to detect infections with Moraxella catarrhalis, and for the development of methods for detection of antigens in samples from the respiratory tract.

Citing Articles

Branhamella catarrhalis: epidemiology, surface antigenic structure, and immune response.

Murphy T Microbiol Rev. 1996; 60(2):267-79.

PMID: 8801433 PMC: 239443. DOI: 10.1128/mr.60.2.267-279.1996.

A monoclonal antibody reactive with a common epitope of Moraxella (Branhamella) catarrhalis lipopolysaccharides.

Oishi K, Tanaka H, Sonoda F, Borann S, Ahmed K, Utsunomiya Y Clin Diagn Lab Immunol. 1996; 3(3):351-4.

PMID: 8705682 PMC: 170345. DOI: 10.1128/cdli.3.3.351-354.1996.

Maternal antibodies and acquired serological response to Moraxella catarrhalis in children determined by an enzyme-linked immunosorbent assay.

Ejlertsen T, Thisted E, Ostergaard P, Renneberg J Clin Diagn Lab Immunol. 1994; 1(4):464-8.

PMID: 8556485 PMC: 368290. DOI: 10.1128/cdli.1.4.464-468.1994.

Lack of serotype-specific antibody response to lipopolysaccharide antigens of Moraxella catarrhalis during lower respiratory tract infection.

Rahman M, Holme T, Jonsson I, Krook A Eur J Clin Microbiol Infect Dis. 1995; 14(4):297-304.

PMID: 7649192 DOI: 10.1007/BF02116522.

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