Carrier-mediated Residual K+ and Na+ Transport of Human Red Blood Cells

Overview

Journal J Membr Biol

Date 1993 Mar 1

PMID 8496945

Citations 3

Authors

K Denner

R Heinrich

I Bernhardt

Affiliations

Soon will be listed here.

Abstract

Residual, i.e., (ouabain, bumetanide, and EGTA)-insensitive K+ and Na+ influxes as well as effluxes of human red blood cells are enhanced in isotonic solutions of low (NaCl + KCl) concentration using sucrose to maintain constant osmolarity. Various carrier models were tested to fit the experimental data of these fluxes simultaneously. The residual K+ and Na+ fluxes can be described on the basis of a carrier mechanism of competing substrates with modifier sites.

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