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Probability of Establishing Chimeric Plasmids in Natural Populations of Bacteria

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Journal Science
Specialty Science
Date 1977 Apr 8
PMID 847470
Citations 7
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Abstract

Formulas for estimating the probability that chimeric plasmids carried by disarmed hosts will become established in natural populations of bacteria are presented and their use illustrated with a series of realistic numerical examples. The implications of these a priori probability estimates for the problem of containment for recombinant DNA research is discussed.

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