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Synthesis of New Steroid Haptens for Radioimmunoassay. Part III. 15beta-Carboxyethylmercaptosteroid-bovine Serum Albumin Conjugates. Specific Antisera for Radioimmunoassay of 5alpha-dihydrotestosterone, 5alpha-androstane-3beta, 17beta-diol And...

Overview
Journal Steroids
Publisher Elsevier
Specialty Biochemistry
Date 1977 Feb 1
PMID 841620
Citations 6
Authors
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Abstract

The syntheses of 15beta-carboxyethylmercapto-5alpha-dihydrotestosterone, 15beta-carbosyethylmercapto-5alpha-androstane-3beta, 17beta-diol and 15beta-carboxyethylmercapto-5alpha-androstane-3alpha, 17beta-diol and the preparation of their bovine serum albumin (BSA) conjugates are described. These conjugates were employed for the generation of specific antisera suitable for radioimmunoassay (RIA) of 5alpha-dihydrotestosterone (5alpha-DHT), 5alpha-androstane-3beta, 17beta-diol (3beta-diol) and 5alpha-androstane-3alpha, 17beta-diol (3alpha-diol).

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