Roles of Leukotriene B4, Prostaglandin E2, and Cyclic AMP in Campylobacter Jejuni-induced Intestinal Fluid Secretion

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1993 Nov 1

PMID 8406889

Citations 7

Authors

P H Everest

A T Cole

C J Hawkey

S Knutton

H Goossens

J P Butzler

J M Ketley

P H Williams

Affiliations

Soon will be listed here.

Abstract

Infection of rabbit ileal loops with inflammatory Campylobacter jejuni strains caused elevation of cyclic AMP, prostaglandin E2, and leukotriene B4 levels in tissue and fluids. Incubation of cultured Caco-2 cells with loop fluids caused elevated cellular cyclic AMP levels, an effect which was inhibited by antiserum against prostaglandin E2.

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