Monocyte Antimycobacterial Activity Before and After Mycobacterium Bovis BCG Vaccination in Chingleput, India, and London, United Kingdom

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1993 Oct 1

PMID 8406843

Citations 4

Authors

S H Cheng

K B Walker

D B Lowrie

D A Mitchison

R Swamy

M Datta

R Prabhakar

Affiliations

Soon will be listed here.

Abstract

Monocytes from purified protein derivative S Mantoux-negative children and young adults inhibited intracellular growth of Mycobacterium microti more in Chingleput than in London. Mycobacterium bovis BCG vaccination did not enhance bacteriostasis with the Indians but did so with the Londoners. No evidence was found for involvement of cytokines such as macrophage-activating factor and granulocyte macrophage colony-stimulating factor in the differences.

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