Adult Onset Still's Disease and Pregnancy
Overview
Affiliations
The interactions between pregnancy and adult onset Still's disease (AOSD) are unclear. Between 1983 and 1990, 5 pregnancies occurred in 4 women with AOSD. AOSD occurred at the 5th and 6th month of the 1st pregnancy in 2 patients; a 2nd pregnancy occurring in one of them was not associated with a flare. In the other 2 patients pregnancy occurred 36 and 44 months after the AOSD; during gestation only transient arthralgia were observed in both cases. Pregnancy seems to have no effect on AOSD, and conversely, in our experience, AOSD has no influence on pregnancy, fetal growth or infant health.
A rare case of adult-onset Still's disease presenting in the early postpartum period.
Lieschke A, Hasnol M, Martin A, Tsai T Obstet Med. 2025; 18(1):50-53.
PMID: 39959002 PMC: 11826871. DOI: 10.1177/1753495X231172541.
Pregnancy-Associated Onset of Adult-Onset Still's Disease.
Zayat N, Arora A, OBrien J, Bal J, Sugarman R, Rivera L AJP Rep. 2024; 14(2):e145-e155.
PMID: 38799549 PMC: 11126333. DOI: 10.1055/a-2318-0305.
Adult-onset Still's Disease during Pregnancy Treated with Tocilizumab.
Imaizumi C, Saito M, Abe F, Kaga H, Saito A, Nara M Intern Med. 2022; 61(20):3137-3140.
PMID: 35283384 PMC: 9646338. DOI: 10.2169/internalmedicine.8886-21.
Hosoya S, Sadatsuki M, Izuka S, Yamashita H, Oishi H BMC Pregnancy Childbirth. 2021; 21(1):163.
PMID: 33627085 PMC: 7905546. DOI: 10.1186/s12884-021-03648-1.
Pregnancy Outcomes in Patients With Adult-Onset Still's Disease: A Cohort Study From China.
Wang Z, Chi H, Feng T, Du Q, Zeng T, Teng J Front Med (Lausanne). 2020; 7:566738.
PMID: 33364243 PMC: 7753176. DOI: 10.3389/fmed.2020.566738.