Non-injection Methods for the Production of Embryonic Stem Cell-embryo Chimaeras

Overview

Journal Nature

Specialty Science

Date 1993 Sep 2

PMID 8361547

Citations 61

Authors

S A Wood

N D Allen

J Rossant

A Auerbach

A Nagy

Affiliations

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Abstract

The simple aggregation of pluripotent ES cells with morulae-stage embryos can result in viable chimaeras at a similar frequency to that of blastocyst injection. The savings in time and equipment inherent in the aggregation techniques, however, make this approach well worth considering.

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