Hirschsprung's Disease: Clinical and Experimental Observations
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Hirschsprung's disease (HD) is a relatively common cause of intestinal obstruction in the newborn. It is characterized by an absence of ganglion cells in the distal bowel beginning at the internal sphincter and extending proximally for varying distances. The etiology of HD-associated enterocolitis remains a complex issue. This study has provided further support for a possible infectious etiology of enterocolitis complicating HD.
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Khan A, Vujanic G, Huddart S Pediatr Surg Int. 2003; 19(6):439-42.
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Role of nitric oxide in the internal anal sphincter of Hirschsprung's disease.
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PMID: 12370788 DOI: 10.1007/s00268-002-6384-7.