Slowly Progressive Apraxia: Two Case Studies

Overview

Journal J Neurol

Specialty Neurology

Date 1993 Jun 1

PMID 8336174

Citations 5

Authors

P Azouvi

C Bergego

L Robel

N Marlier

I Durand

J P HELD

B Bussel

Affiliations

Soon will be listed here.

Abstract

Two patients with a slowly progressive and severe motor apraxia are presented. In one case, there was only apraxia; in the other there was moderate memory disturbance and a mild decline of global intellectual ability, suggesting a more widespread cognitive dysfunction. In this second case, recognition of the correct use of objects was also severely impaired, suggesting a disturbance of motor knowledge. In both cases, apraxia was asymmetrical, and associated with a contralateral atrophy of the upper parietal cortex, suggesting a differential involvement of separate action systems for each hand.

Citing Articles

Apraxia phenotypes and frontotemporal lobar degeneration.

Langheinrich T, Thompson J, Jones M, Richardson A, Mann D, Snowden J J Neurol. 2024; 271(12):7471-7488.

PMID: 39387948 PMC: 11588949. DOI: 10.1007/s00415-024-12706-5.

The Progressive Acalculia Presentation of Parietal Variant Alzheimer's Disease.

Mendez M, Moheb N, Desarzant R, Teng E J Alzheimers Dis. 2018; 63(3):941-948.

PMID: 29710718 PMC: 6535210. DOI: 10.3233/JAD-180024.

Progressive transcortical sensory aphasia and progressive ideational apraxia owing to temporoparietal cortical atrophy.

Funayama M, Nakajima A BMC Neurol. 2015; 15:231.

PMID: 26559349 PMC: 4642747. DOI: 10.1186/s12883-015-0490-2.

Posterior cortical atrophy: variant of Alzheimer's disease? A case series with PET findings.

Schmidtke K, Hull M, Talazko J J Neurol. 2005; 252(1):27-35.

PMID: 15654552 DOI: 10.1007/s00415-005-0594-5.

Slowly progressive apraxia in Alzheimer's disease.

Green R, Goldstein F, Mirra S, Alazraki N, Baxt J, Bakay R J Neurol Neurosurg Psychiatry. 1995; 59(3):312-5.

PMID: 7673964 PMC: 486038. DOI: 10.1136/jnnp.59.3.312.

References

Graff-Radford N, Damasio A, Hyman B, Hart M, Tranel D, Damasio H . Progressive aphasia in a patient with Pick's disease: a neuropsychological, radiologic, and anatomic study. Neurology. 1990; 40(4):620-6. DOI: 10.1212/wnl.40.4.620. View

Cambier J, Masson M, Dairou R, Henin D . [A parietal form of Pick's disease: clinical and pathological study (author's transl)]. Rev Neurol (Paris). 1981; 137(1):33-8. View

Kirshner H, Tanridag O, THURMAN L, Whetsell Jr W . Progressive aphasia without dementia: two cases with focal spongiform degeneration. Ann Neurol. 1987; 22(4):527-32. DOI: 10.1002/ana.410220413. View

Mesulam M . Slowly progressive aphasia without generalized dementia. Ann Neurol. 1982; 11(6):592-8. DOI: 10.1002/ana.410110607. View

POECK K . The clinical examination for motor apraxia. Neuropsychologia. 1986; 24(1):129-34. DOI: 10.1016/0028-3932(86)90046-1. View

Mesulam M . Primary progressive aphasia--differentiation from Alzheimer's disease. Ann Neurol. 1987; 22(4):533-4. DOI: 10.1002/ana.410220414. View

Laplane D, Degos J . Motor neglect. J Neurol Neurosurg Psychiatry. 1983; 46(2):152-8. PMC: 1027298. DOI: 10.1136/jnnp.46.2.152. View

POECK K, Lehmkuhl G . Ideatory apraxia in a left-handed patient with right-sided brain lesion. Cortex. 1980; 16(2):273-84. DOI: 10.1016/s0010-9452(80)80062-1. View

Crystal H, Horoupian D, Katzman R, Jotkowitz S . Biopsy-proved Alzheimer disease presenting as a right parietal lobe syndrome. Ann Neurol. 1982; 12(2):186-8. DOI: 10.1002/ana.410120210. View

10.

De Renzi E . Slowly progressive visual agnosia or apraxia without dementia. Cortex. 1986; 22(1):171-80. DOI: 10.1016/s0010-9452(86)80041-7. View

11.

Geschwind N . Disconnexion syndromes in animals and man. I. Brain. 1965; 88(2):237-94. DOI: 10.1093/brain/88.2.237. View

12.

Leger J, Levasseur M, Benoit N, Baron J, Tran Dinh S, Bolgert F . [Slowly progressive apraxia: a MRI and positron tomography in 4 cases]. Rev Neurol (Paris). 1991; 147(3):183-91. View

13.

POECK K, Luzzatti C . Slowly progressive aphasia in three patients. The problem of accompanying neuropsychological deficit. Brain. 1988; 111 ( Pt 1):151-68. DOI: 10.1093/brain/111.1.151. View

14.

Benson D, Cummings J . Angular gyrus syndrome simulating Alzheimer's disease. Arch Neurol. 1982; 39(10):616-20. DOI: 10.1001/archneur.1982.00510220014003. View

15.

HECAEN H, GIMENO ALAVA A . [Left unilateral ideomotor apraxia]. Rev Neurol (Paris). 1960; 102:648-53. View

16.

De Renzi E, Lucchelli F . Ideational apraxia. Brain. 1988; 111 ( Pt 5):1173-85. DOI: 10.1093/brain/111.5.1173. View

17.

Heilman K, Rothi L, Valenstein E . Two forms of ideomotor apraxia. Neurology. 1982; 32(4):342-6. DOI: 10.1212/wnl.32.4.342. View

18.

Benson D, Davis R, Snyder B . Posterior cortical atrophy. Arch Neurol. 1988; 45(7):789-93. DOI: 10.1001/archneur.1988.00520310107024. View

19.

Magnani G, Bettoni L, Mazzucchi A . [Bioccipital atrophic lesions of uncertain nature at the source of visual agnosia]. Riv Neurol. 1982; 52(3):137-48. View

20.

Freedman L, Selchen D, Black S, Kaplan R, Garnett E, Nahmias C . Posterior cortical dementia with alexia: neurobehavioural, MRI, and PET findings. J Neurol Neurosurg Psychiatry. 1991; 54(5):443-8. PMC: 488546. DOI: 10.1136/jnnp.54.5.443. View