Heterogeneous Surface Distribution of the Fibrinogen-binding Protein on Candida Albicans

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1994 Feb 1

PMID 8300229

Citations 13

Authors

J P Martinez

J L Lopez-Ribot

W L Chaffin

Affiliations

Soon will be listed here.

Abstract

As detected by indirect immunofluorescence and confocal microscopy, fibrinogen binding was heterogeneously distributed on the surface of Candida albicans. A low level of binding was generally observed homogeneously distributed on some yeast and most hyphal extensions of germ tubes. However, on most hyphal extensions, there were randomly distributed areas of increased expression, as revealed by patches of greater fluorescence intensity.

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References

Casanova M, Martinez J, Chaffin W . Fab fragments from a monoclonal antibody against a germ tube mannoprotein block the yeast-to-mycelium transition in Candida albicans. Infect Immun. 1990; 58(11):3810-2. PMC: 313733. DOI: 10.1128/iai.58.11.3810-3812.1990. View

Mayer C, DIAMOND R, Edwards Jr J . Recognition of binding sites on Candida albicans by monoclonal antibodies to human leukocyte antigens. Infect Immun. 1990; 58(11):3765-9. PMC: 313726. DOI: 10.1128/iai.58.11.3765-3769.1990. View

Calderone R, Braun P . Adherence and receptor relationships of Candida albicans. Microbiol Rev. 1991; 55(1):1-20. PMC: 372798. DOI: 10.1128/mr.55.1.1-20.1991. View

Lopez-Ribot J, Casanova M, Martinez J, Sentandreu R . Characterization of cell wall proteins of yeast and hydrophobic mycelial cells of Candida albicans. Infect Immun. 1991; 59(7):2324-32. PMC: 258014. DOI: 10.1128/iai.59.7.2324-2332.1991. View

Casanova M, Lopez-Ribot J, Monteagudo C, Llombart-Bosch A, Sentandreu R, Martinez J . Identification of a 58-kilodalton cell surface fibrinogen-binding mannoprotein from Candida albicans. Infect Immun. 1992; 60(10):4221-9. PMC: 257456. DOI: 10.1128/iai.60.10.4221-4229.1992. View

Lee K, Buckley H, CAMPBELL C . An amino acid liquid synthetic medium for the development of mycelial and yeast forms of Candida Albicans. Sabouraudia. 1975; 13(2):148-53. DOI: 10.1080/00362177585190271. View

Koch Y, Rademacher K . Chemical and enzymatic changes in the cell walls of Candida albicans and Saccharomyces cerevisiae by scanning electron microscopy. Can J Microbiol. 1980; 26(8):965-70. DOI: 10.1139/m80-164. View

Bouali A, Robert R, Tronchin G, Senet J . Binding of human fibrinogen to Candida albicans in vitro: a preliminary study. J Med Vet Mycol. 1986; 24(4):345-8. DOI: 10.1080/02681218680000511. View

Tronchin G, Robert R, Bouali A, Senet J . Immunocytochemical localization of in vitro binding of human fibrinogen to Candida albicans germ tube and mycelium. Ann Inst Pasteur Microbiol. 1987; 138(2):177-87. DOI: 10.1016/0769-2609(87)90194-3. View

10.

Bouali A, Robert R, Tronchin G, Senet J . Characterization of binding of human fibrinogen to the surface of germ-tubes and mycelium of candida albicans. J Gen Microbiol. 1987; 133(3):545-51. DOI: 10.1099/00221287-133-3-545. View

11.

Anderson J, Soll D . Unique phenotype of opaque cells in the white-opaque transition of Candida albicans. J Bacteriol. 1987; 169(12):5579-88. PMC: 213989. DOI: 10.1128/jb.169.12.5579-5588.1987. View

12.

Chaffin W, Skudlarek J, Morrow K . Variable expression of a surface determinant during proliferation of Candida albicans. Infect Immun. 1988; 56(2):302-9. PMC: 259280. DOI: 10.1128/iai.56.2.302-309.1988. View

13.

Chaffin W, Ringler L, Larsen H . Interactions of monospecific antisera with cell surface determinants of Candida albicans. Infect Immun. 1988; 56(12):3294-6. PMC: 259737. DOI: 10.1128/iai.56.12.3294-3296.1988. View

14.

Casanova M, Gil M, Cardenoso L, Martinez J, Sentandreu R . Identification of wall-specific antigens synthesized during germ tube formation by Candida albicans. Infect Immun. 1989; 57(1):262-71. PMC: 313084. DOI: 10.1128/iai.57.1.262-271.1989. View

15.

Anderson J, Cundiff L, Schnars B, Gao M, Mackenzie I, Soll D . Hypha formation in the white-opaque transition of Candida albicans. Infect Immun. 1989; 57(2):458-67. PMC: 313119. DOI: 10.1128/iai.57.2.458-467.1989. View

16.

Page S, Odds F . Binding of plasma proteins to Candida species in vitro. J Gen Microbiol. 1988; 134(10):2693-702. DOI: 10.1099/00221287-134-10-2693. View

17.

Cassone A . Cell wall of Candida albicans: its functions and its impact on the host. Curr Top Med Mycol. 1989; 3:248-314. DOI: 10.1007/978-1-4612-3624-5_10. View

18.

Bouchara J, Tronchin G, Annaix V, Robert R, Senet J . Laminin receptors on Candida albicans germ tubes. Infect Immun. 1990; 58(1):48-54. PMC: 258407. DOI: 10.1128/iai.58.1.48-54.1990. View

19.

Kanbe T, Li R, Wadsworth E, Calderone R, Cutler J . Evidence for expression of the C3d receptor of Candida albicans in vitro and in vivo obtained by immunofluorescence and immunoelectron microscopy. Infect Immun. 1991; 59(5):1832-8. PMC: 257923. DOI: 10.1128/iai.59.5.1832-1838.1991. View