Adaptation of a Microimmunofluorescence Test to the Study of Human Rickettsia Tsutsugamuskh Antibody

Overview

Journal Am J Trop Med Hyg

Specialty Tropical Medicine

Date 1976 Nov 1

PMID 827214

Citations 30

Authors

D M Robinson

G Brown

E Gan

D L Huxsoll

Affiliations

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Abstract

A microimmunofluorescence (micro-IFA) test has been adapted to the study of naturally occurring antibody to Rickettsia tsutsugamushi in humans. The micro-IFA test was comparable to the present immlnofluorescent assay in sensitivity and reproducibility, but offered distinct advantages in the quantity of reagents necessary. Also the micro-IFA could be used to simultaneously titer a serum to as many as nine strains of the organism resulting in a great saving of time.

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