Multiple Organ Failure After Mitral Valve Repair with Intravascular Hemolysis and Its Recovery Due to Mitral Valve Replacement
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We present a patient with evidence of severe intravascular hemolysis after mitral valve repair, an established method for the surgical treatment of mitral valve disease to avoid prosthesis related complications. The coincidence of this uncommon complication with hemodynamic instability due to pre-existing myocardial dysfunction and Gram-negative pneumonia promoted the development of simultaneous dysfunction of liver, kidney and the cardio-respiratory system. Elimination of the source of hemolysis by re-operation with mitral valve replacement on the ninth postoperative day allowed prompt recovery from severe organ dysfunction. Free hemoglobin may have perpetuated progressive organ failure in our patient.
Reoperation after mitral valve repair in viewpoints of kidney injury as well as hemolytic anemia.
Ishida R, Adachi T, Shiotsu Y, Ishida M, Mori Y, Doi K CEN Case Rep. 2017; 4(2):119-125.
PMID: 28509086 PMC: 5411629. DOI: 10.1007/s13730-014-0152-z.
Hemolytic anemia following mitral valve repair: A case presentation and literature review.
Abourjaili G, Torbey E, Alsaghir T, Olkovski Y, Costantino T Exp Clin Cardiol. 2013; 17(4):248-50.
PMID: 23592946 PMC: 3627285.