Hypertension and the J-curve. How Low Should You Go?
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Recent analyses of treated blood pressure versus events suggest that drug treatment might result in an increase in coronary events or mortality at treated diastolic pressures below 80 mm Hg (the "J-curve"). However, this contention is highly controversial. Both sides of the argument are examined and a balanced approach for target blood pressure goals on treatment is outlined.
How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data.
Yashin A, Arbeev K, Wu D, Arbeeva L, Kulminski A, Akushevich I Front Genet. 2013; 4:3.
PMID: 23346098 PMC: 3551204. DOI: 10.3389/fgene.2013.00003.