Rous-Whipple Award Lecture. Atherosclerosis: a Defense Mechanism Gone Awry

Overview

Journal Am J Pathol

Publisher Elsevier

Specialty Pathology

Date 1993 Oct 1

PMID 8214014

Citations 47

Authors

R Ross

Affiliations

Soon will be listed here.

Citing Articles

OxLDL/LOX-1 mediated sex, age, stiffness, and endothelial dependent alterations in mouse thoracic aortic vascular reactivity.

Wendt T, Ansar S, Gonzales R Front Physiol. 2024; 15:1471272.

PMID: 39563936 PMC: 11573510. DOI: 10.3389/fphys.2024.1471272.

Intimomedial tears of the aorta heal by smooth muscle cell-mediated fibrosis without atherosclerosis.

Hassab A, Hur D, Vallabhajosyula P, Tellides G, Assi R JCI Insight. 2024; 9(9).

PMID: 38592807 PMC: 11141924. DOI: 10.1172/jci.insight.172437.

The Ratio of Red Blood Cell Distribution Width to Albumin Is Correlated With All-Cause Mortality of Patients After Percutaneous Coronary Intervention - A Retrospective Cohort Study.

Weng Y, Peng Y, Xu Y, Wang L, Wu B, Xiang H Front Cardiovasc Med. 2022; 9:869816.

PMID: 35686040 PMC: 9170887. DOI: 10.3389/fcvm.2022.869816.

Aortic intimal resident macrophages are essential for maintenance of the non-thrombogenic intravascular state.

Hernandez G, Ma F, Martinez G, Firozabadi N, Salvador J, Juang L Nat Cardiovasc Res. 2022; 1(1):67-84.

PMID: 35599984 PMC: 9121812. DOI: 10.1038/s44161-021-00006-4.

Diversity of Lipid Function in Atherogenesis: A Focus on Endothelial Mechanobiology.

Kotlyarov S Int J Mol Sci. 2021; 22(21).

PMID: 34768974 PMC: 8584259. DOI: 10.3390/ijms222111545.

References

Cushing S, Berliner J, Valente A, Territo M, Navab M, Parhami F . Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci U S A. 1990; 87(13):5134-8. PMC: 54276. DOI: 10.1073/pnas.87.13.5134. View

Carlos T, Harlan J . Membrane proteins involved in phagocyte adherence to endothelium. Immunol Rev. 1990; 114:5-28. DOI: 10.1111/j.1600-065x.1990.tb00559.x. View

Springer T . Adhesion receptors of the immune system. Nature. 1990; 346(6283):425-34. DOI: 10.1038/346425a0. View

Xu Q, Oberhuber G, Gruschwitz M, Wick G . Immunology of atherosclerosis: cellular composition and major histocompatibility complex class II antigen expression in aortic intima, fatty streaks, and atherosclerotic plaques in young and aged human specimens. Clin Immunol Immunopathol. 1990; 56(3):344-59. DOI: 10.1016/0090-1229(90)90155-j. View

Yla-Herttuala S, Rosenfeld M, Parthasarathy S, Glass C, Sigal E, Witztum J . Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions. Proc Natl Acad Sci U S A. 1990; 87(18):6959-63. PMC: 54661. DOI: 10.1073/pnas.87.18.6959. View

Rosenfeld M, Ross R . Macrophage and smooth muscle cell proliferation in atherosclerotic lesions of WHHL and comparably hypercholesterolemic fat-fed rabbits. Arteriosclerosis. 1990; 10(5):680-7. DOI: 10.1161/01.atv.10.5.680. View

Moses H, Yang E, Pietenpol J . TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights. Cell. 1990; 63(2):245-7. DOI: 10.1016/0092-8674(90)90155-8. View

Brown G, Albers J, Fisher L, Schaefer S, Lin J, Kaplan C . Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. N Engl J Med. 1990; 323(19):1289-98. DOI: 10.1056/NEJM199011083231901. View

Battegay E, Raines E, Seifert R, Bowen-Pope D, Ross R . TGF-beta induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell. 1990; 63(3):515-24. DOI: 10.1016/0092-8674(90)90448-n. View

10.

Steinbrecher U, Zhang H, Lougheed M . Role of oxidatively modified LDL in atherosclerosis. Free Radic Biol Med. 1990; 9(2):155-68. DOI: 10.1016/0891-5849(90)90119-4. View

11.

Carlos T, Dobrina A, Ross R, Harlan J . Multiple receptors on human monocytes are involved in adhesion to cultured human endothelial cells. J Leukoc Biol. 1990; 48(5):451-6. DOI: 10.1002/jlb.48.5.451. View

12.

Koch A, Haines G, Rizzo R, Radosevich J, Pope R, Robinson P . Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated response. Am J Pathol. 1990; 137(5):1199-213. PMC: 1877681. View

13.

Kane J, Malloy M, Ports T, Phillips N, DIEHL J, HAVEL R . Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens. JAMA. 1990; 264(23):3007-12. View

14.

Rosenfeld M, Khoo J, Miller E, Parthasarathy S, Palinski W, Witztum J . Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts. J Clin Invest. 1991; 87(1):90-9. PMC: 294999. DOI: 10.1172/JCI115006. View

15.

Libby P, Hansson G . Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. Lab Invest. 1991; 64(1):5-15. View

16.

Cybulsky M, Gimbrone Jr M . Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 1991; 251(4995):788-91. DOI: 10.1126/science.1990440. View

17.

Tagawa H, Tomoike H, Nakamura M . Putative mechanisms of the impairment of endothelium-dependent relaxation of the aorta with atheromatous plaque in heritable hyperlipidemic rabbits. Circ Res. 1991; 68(2):330-7. DOI: 10.1161/01.res.68.2.330. View

18.

Bucala R, Tracey K, Cerami A . Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes. J Clin Invest. 1991; 87(2):432-8. PMC: 295094. DOI: 10.1172/JCI115014. View

19.

Minick C, MURPHY G, CAMPBELL Jr W . Experimental induction of athero-arteriosclerosis by the synergy of allergic injury to arteries and lipid-rich diet. I. Effect of repeated injections of horse serum in rabbits fed a dietary cholesterol supplement. J Exp Med. 1966; 124(4):635-52. PMC: 2138247. DOI: 10.1084/jem.124.4.635. View

20.

French J . Atherosclerosis in relation to the structure and function of the arterial intima, with special reference to th endothelium. Int Rev Exp Pathol. 1966; 5:253-353. View