Primary Rhabdomyosarcoma of the Iliac Bone in an Adult: a Case Mimicking Fibrosarcoma

Overview

Journal Virchows Arch A Pathol Anat Histopathol

Specialty Anatomy & Histology

Date 1993 Jan 1

PMID 8212536

Citations 3

Authors

Y Oda

M Tsuneyoshi

H Hashimoto

T Iwashita

M Ushijima

S Masuda

Y Iwamoto

Y Sugioka

Affiliations

Soon will be listed here.

Abstract

Primary rhabdomyosarcoma of bone is exceedingly rare. We present a case of rhabdomyosarcoma of the iliac bone in a 32-year-old male. Histologically, the tumour consisted mainly of a uniform proliferation of elongated spindle cells arranged in a herring bone pattern, simulating fibrosarcoma. Focally there was a conventional embryonal pattern with scattered rhabdomyoblasts possessing an eosinophilic cytoplasm. Immunohistochemical studies disclosed expression of muscle markers such as desmin and muscle-specific actin, in both the embryonal and spindle-cell areas and myoglobin only in the embryonal areas. Such histological features are unusual for classical embryonal rhabdomyosarcoma. The anatomical site and age of the patient are also atypical.

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