Nonpalpable Breast Tumors: Diagnosis with Contrast-enhanced Subtraction Dynamic MR Imaging

Overview

Journal Radiology

Specialty Radiology

Date 1994 Jun 1

PMID 8184038

Citations 33

Authors

R Gilles

J M Guinebretiere

O Lucidarme

P Cluzel

G Janaud

J F Finet

A Tardivon

J MASSELOT

D Vanel

Affiliations

Soon will be listed here.

Abstract

Purpose: To determine the accuracy of contrast material-enhanced subtraction dynamic magnetic resonance (MR) imaging in the diagnosis of nonpalpable breast tumors.

Materials And Methods: One hundred forty-three patients underwent surgical biopsy of a nonpalpable breast lesion. Their mammograms showed microcalcifications (n = 80), opacity (n = 52), architectural distortion (n = 10), or asymmetric density (n = 1). All patients underwent a preoperative gadolinium tetraazacyclododecanetetraacetic acid-enhanced subtraction dynamic study. Any early contrast enhancement in the breast parenchyma was considered pathologic.

Results: At histologic analysis, 27 intraductal carcinomas, 37 invasive carcinomas, and 79 benign lesions were found. Dynamic MR studies showed early contrast enhancement in 61 of 64 breast cancers (sensitivity, 95%) and in 37 of 79 benign lesions (specificity, 53%). Two invasive lobular carcinomas and one tubular carcinoma showed no early contrast enhancement.

Conclusion: Subtraction dynamic MR imaging may be helpful to rule out malignancy in nonpalpable breast tumors.

Citing Articles

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