Studies on the Antimicrobial Activity of Amniotic Fluid

Overview

Journal Am J Obstet Gynecol

Publisher Elsevier

Specialty Gynecology & Obstetrics

Date 1976 May 15

PMID 817602

Citations 8

Authors

J Miller

J Michel

B BERCOVICI

M ARGAMAN

T Sacks

Affiliations

Soon will be listed here.

Abstract

Sixty-one amniotic fluid samples from women in their second and third trimesters of pregnancy were examined for antimicrobial activity. Seventy per cent of the fluids were found to be active. The factor or factors responsible for this activity were present in low concentrations. The presence of spermine in the fluids accounted for some of the antimicrobial activity.

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PMID: 37422429 PMC: 10530449. DOI: 10.1016/j.humimm.2023.06.005.

Human β-defensin-3 participates in intra-amniotic host defense in women with labor at term, spontaneous preterm labor and intact membranes, and preterm prelabor rupture of membranes.

Para R, Romero R, Miller D, Panaitescu B, Varrey A, Chaiworapongsa T J Matern Fetal Neonatal Med. 2019; 33(24):4117-4132.

PMID: 30999788 PMC: 6800590. DOI: 10.1080/14767058.2019.1597047.

Human β-defensin-1: A natural antimicrobial peptide present in amniotic fluid that is increased in spontaneous preterm labor with intra-amniotic infection.

Varrey A, Romero R, Panaitescu B, Miller D, Chaiworapongsa T, Patwardhan M Am J Reprod Immunol. 2018; 80(4):e13031.

PMID: 30101464 PMC: 6160339. DOI: 10.1111/aji.13031.

The diagnostic performance of the beta-glucan assay in the detection of intra-amniotic infection with Candida species.

Pacora P, Romero R, Erez O, Maymon E, Panaitescu B, Kusanovic J J Matern Fetal Neonatal Med. 2017; 32(10):1703-1720.

PMID: 29226760 PMC: 6021224. DOI: 10.1080/14767058.2017.1416083.

Novel antibacterial activity of β(2)-microglobulin in human amniotic fluid.

Kim J, Park S, Lee J, Choi S, Hahm K, Park Y PLoS One. 2012; 7(11):e47642.

PMID: 23144825 PMC: 3492387. DOI: 10.1371/journal.pone.0047642.