Evidence for a New Type of Complementation Among the Cin, Lxd and Ma-l Loci in Drosophila Melanogaster
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Molecular Biology
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A phenotypic effect of the lxd locus in the expression of the cin and ma-l gene products has been described. Flies which are genotypically lxd have normal eye pigments, but maternally affected cin; lxd or ma-l; lxd flies are characterized by mutant eyes which are indistinguishable from those observed in ma-l or ry mutant strains. Furthermore, under ocnditions where there is only partial complementation at the ma-l locus, the presence of the lxd gene is sufficient to prevent normal eye pigmentation. The possibility that these post translational interactions of the cin, lxd, and ma-l loci may prove useful in the isolation of additional loci affecting XDH synthesis is discussed.
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