Ehrlichia Chaffeensis Expresses an Immunoreactive Protein Homologous to the Escherichia Coli GroEL Protein

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1993 Aug 1

PMID 8101510

Citations 19

Authors

J W Sumner

K G Sims

D C Jones

B E Anderson

Affiliations

Soon will be listed here.

Abstract

A clone expressing a 58-kDa protein reactive with human convalescent-phase serum was isolated from a recombinant library of Ehrlichia chaffeensis, the etiologic agent of human ehrlichiosis. Sequencing identified two open reading frames, one encoding a 10.3-kDa polypeptide consisting of 94 amino acids and another encoding a 58-kDa polypeptide consisting of 550 amino acids. The sequences of the 10.3- and 58-kDa polypeptides were homologous to those of the Escherichia coli GroES and GroEL heat shock proteins, respectively.

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