Regional Retinal Blood Flow Reduction Following Half Fundus Photocoagulation Treatment

Overview

Journal Br J Ophthalmol

Specialty Ophthalmology

Date 1994 May 1

PMID 8025063

Citations 8

Authors

N Fujio

G T Feke

D G Goger

J W McMeel

Affiliations

Soon will be listed here.

Abstract

Regional changes in retinal blood flow following inferior and subsequent superior argon laser half fundus photocoagulation treatment were measured in six diabetic patients with advanced retinopathy. Centreline blood velocity, vessel diameter, and blood flow in major inferior and superior temporal retinal arteries were measured at baseline and following each treatment using the bidirectional laser Doppler technique and monochromatic fundus photography. Inferior fundus laser treatment produced a significant blood flow decrease in inferior temporal arteries ranging from 60% to 78%. Blood flow changes in superior temporal arteries were not significant, ranging from -7% to +14%. Subsequent superior fundus laser treatment produced a significant blood flow decrease in superior temporal arteries ranging from 50% to 66%. Subsequent blood flow changes in inferior temporal arteries were not significant, ranging from -19% to +21%. The results indicate that regional laser treatment produces a regional reduction in retinal blood flow, consistent with measurements of preretinal and intraretinal oxygen tension which have indicated increases in oxygen over photocoagulated regions.

Citing Articles

Association of changes of retinal vessels diameter with ocular blood flow in eyes with diabetic retinopathy.

Ueno Y, Iwase T, Goto K, Tomita R, Ra E, Yamamoto K Sci Rep. 2021; 11(1):4653.

PMID: 33633255 PMC: 7907275. DOI: 10.1038/s41598-021-84067-2.

Evaluation of blood flow on optic nerve head after pattern scan and conventional laser panretinal photocoagulation.

Iwase T, Mikoshiba Y, Ra E, Yamamoto K, Ueno Y, Terasaki H Medicine (Baltimore). 2019; 98(24):e16062.

PMID: 31192968 PMC: 6587595. DOI: 10.1097/MD.0000000000016062.

Retinal blood flow reduction after panretinal photocoagulation in Type 2 diabetes mellitus: Doppler optical coherence tomography flowmeter pilot study.

Song Y, Tani T, Omae T, Ishibazawa A, Yoshioka T, Takahashi K PLoS One. 2018; 13(11):e0207288.

PMID: 30408113 PMC: 6224130. DOI: 10.1371/journal.pone.0207288.

A randomized clinical trial evaluating choroidal blood flow and morphology after conventional and pattern scan laser panretinal photocoagulation.

Mikoshiba Y, Iwase T, Ueno Y, Yamamoto K, Ra E, Terasaki H Sci Rep. 2018; 8(1):14128.

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Effects of photocoagulation on ocular blood flow in patients with severe non-proliferative diabetic retinopathy.

Iwase T, Kobayashi M, Yamamoto K, Ra E, Terasaki H PLoS One. 2017; 12(3):e0174427.

PMID: 28355247 PMC: 5371365. DOI: 10.1371/journal.pone.0174427.

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