» Articles » PMID: 79807

Absence of a Newly Described Cytochrome B from Neutrophils of Patients with Chronic Granulomatous Disease

Overview
Journal Lancet
Publisher Elsevier
Specialty General Medicine
Date 1978 Aug 26
PMID 79807
Citations 35
Authors
Affiliations
Soon will be listed here.
Abstract

A unique cytochrome b which becomes incorporated into phagocytic vacuoles has been described in human neutrophils. This cytochrome b appears to be situated in the plasma membrane of these cells, and acts as a component of the microbicidal oxidase system. Absence or gross abnormality of this cytochrome b was demonstrated in all four patients with chronic granulomatous disease who were investigated, and reduced concentrations in two mothers known to be carriers of the disease.

Citing Articles

Pharmacological Modulation of Nrf2/HO-1 Signaling Pathway as a Therapeutic Target of Parkinson's Disease.

Wang Y, Gao L, Chen J, Li Q, Huo L, Wang Y Front Pharmacol. 2021; 12:757161.

PMID: 34887759 PMC: 8650509. DOI: 10.3389/fphar.2021.757161.


Beyond the Extra Respiration of Phagocytosis: NADPH Oxidase 2 in Adaptive Immunity and Inflammation.

Mortimer P, Mc Intyre S, Thomas D Front Immunol. 2021; 12:733918.

PMID: 34539670 PMC: 8440999. DOI: 10.3389/fimmu.2021.733918.


The Emerging Roles of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 in Skeletal Muscle Redox Signaling and Metabolism.

Henriquez-Olguin C, Boronat S, Cabello-Verrugio C, Jaimovich E, Hidalgo E, Jensen T Antioxid Redox Signal. 2019; 31(18):1371-1410.

PMID: 31588777 PMC: 6859696. DOI: 10.1089/ars.2018.7678.


NADPH oxidases as electrochemical generators to produce ion fluxes and turgor in fungi, plants and humans.

Segal A Open Biol. 2016; 6(5).

PMID: 27249799 PMC: 4892433. DOI: 10.1098/rsob.160028.


Genetic disorders coupled to ROS deficiency.

ONeill S, Brault J, Stasia M, Knaus U Redox Biol. 2015; 6:135-156.

PMID: 26210446 PMC: 4550764. DOI: 10.1016/j.redox.2015.07.009.