Biochemical Markers for Myocardial Infarction Used in Combination with Clinical Decision Limits. Influence of S-myoglobin on the Predictive Values

To predict the development of an acute myocardial infarction (AMI) in a patient with chest pain or other symptoms compatible with myocardial infarction is a difficult clinical problem. In this study of 927 consecutive patients with a suspected AMI symptoms selected by the Multicenter Chest Pain Study Group were tested. An equation was constructed based on five of the most significant variables found. In a subgroup of 305 patients the additional value of S-Myoglobin was tested and found to be valuable for the decision of further handling of the patient with suspected AMI.