The Use of Agarose Gels for the Assay of the Deoxyribonuclease Activity Associated with the Soluble Penton of Adenoviruses

Overview

Journal Arch Virol

Specialty Microbiology

Date 1976 Jan 1

PMID 797350

Authors

P Medveczky

S CSUZI

I Nasz

E Adam

G BERENCSI

F Antoni

Affiliations

Soon will be listed here.

Abstract

Evidence is presented that the excess pool of penton complexes purified from adenovirus type 1-infected HEp-2 cells also carry an endonucleolytic activity. The effect was measured with both E. coli and adenovirus type 1 double-stranded DNA substrates. The use of agarose gels for assaying the endonuclease activity allowed the approximative calculation of the number of penton molecules which might produce one DNA double-strand break under the experimental conditions selected.

References

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