Protein Folding. Solid Evidence for Molten Globules

Overview

Journal Curr Biol

Publisher Cell Press

Specialty Biology

Date 1994 Jul 1

PMID 7953543

Citations 25

Authors

C M Dobson

Affiliations

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Abstract

Novel experimental strategies are providing details of the structures of non-native states of proteins and shedding light on the concept of a "molten globule" and its relevance to protein folding.

Citing Articles

Pre-Molten, Wet, and Dry Molten Globules en Route to the Functional State of Proteins.

Gupta M, Uversky V Int J Mol Sci. 2023; 24(3).

PMID: 36768742 PMC: 9916686. DOI: 10.3390/ijms24032424.

Molecular Mechanisms of Aggregation of Canine SOD1 E40K Amyloidogenic Mutant Protein.

Wakayama K, Kimura S, Kobatake Y, Kamishina H, Nishii N, Takashima S Molecules. 2023; 28(1).

PMID: 36615350 PMC: 9822309. DOI: 10.3390/molecules28010156.

The Molten Globule State of a Globular Protein in a Cell Is More or Less Frequent Case Rather than an Exception.

Bychkova V, Dolgikh D, Balobanov V, Finkelstein A Molecules. 2022; 27(14).

PMID: 35889244 PMC: 9319461. DOI: 10.3390/molecules27144361.

Life in Phases: Intra- and Inter- Molecular Phase Transitions in Protein Solutions.

Uversky V, Finkelstein A Biomolecules. 2019; 9(12).

PMID: 31817975 PMC: 6995567. DOI: 10.3390/biom9120842.

Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator.

Wang C, Aleksandrov A, Yang Z, Forouhar F, Proctor E, Kota P J Biol Chem. 2018; 293(46):17685-17704.

PMID: 29903914 PMC: 6240863. DOI: 10.1074/jbc.RA117.000819.