Reovirus-like Agent (rotavirus) from Lambs

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1976 Dec 1

PMID 793991

Citations 18

Authors

M S McNulty

G M Allan

G R Pearson

J B McFerran

W L Curran

R M McCracken

Affiliations

Soon will be listed here.

Abstract

Rotavirus particles were demonstrated by electron microscopy in the feces of lambs with diarrhea. Rotavirus antigen was synthesized in cell cultures infected with filtrates of the diarrheic feces, but the virus was not adapted to grow serially in cell cultures. An antigenic relationship between rotaviruses from lambs, pigs, and calves was demonstrated by immunofluorescence. Colostrum-deprived lambs were infected with the lamb rotavirus, and the virus was passaged in lambs. Viral replication occurred in the villous epithelial cells of the small intestine, and the virus was excreted in the feces up to 78 h postinfection. Diarrhea was not observed in the experimentally infected lambs.

Citing Articles

Serological and genomic characterisation of group A rotaviruses from lambs.

Fitzgerald T, Munoz M, Wood A, Snodgrass D Arch Virol. 1995; 140(9):1541-8.

PMID: 7487486 DOI: 10.1007/BF01322528.

Plaque assay of bovine rotavirus.

Butchaiah G, Lund E Acta Vet Scand. 1983; 24(4):362-73.

PMID: 6326542 PMC: 8291256.

Rotaviral antibodies in cow's milk.

Lecce J, King M Can J Comp Med. 1982; 46(4):434-6.

PMID: 6293690 PMC: 1320312.

Shedding of rotavirus in feces of sows before and after farrowing.

Benfield D, Stotz I, MOORE R, McAdaragh J J Clin Microbiol. 1982; 16(1):186-90.

PMID: 6286718 PMC: 272317. DOI: 10.1128/jcm.16.1.186-190.1982.

Viral diarrhea of young animals: a review.

Cilli V, Castrucci G Comp Immunol Microbiol Infect Dis. 1981; 4(3-4):229-42.

PMID: 6277556 PMC: 7133827. DOI: 10.1016/0147-9571(81)90008-4.

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