The Antibiotic Cerulenin, a Novel Tool for Biochemistry As an Inhibitor of Fatty Acid Synthesis

Overview

Journal Bacteriol Rev

Publisher American Society for Microbiology

Specialty Microbiology

Date 1976 Sep 1

PMID 791237

Citations 152

Authors

S Omura

Affiliations

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References

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Omura S, Nakagawa A, Sekikawa K, Otani M, Hata T . Studies on cerulenin. VI. Some spectroscopic features of cerulenin. Chem Pharm Bull (Tokyo). 1969; 17(11):2361-3. DOI: 10.1248/cpb.17.2361. View

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Sato Y, Nomura S, Kamio Y, Omura S, Hata T . Studies on cerulenin, 3. Isolation and physico-chemical properties of cerulenin. J Antibiot (Tokyo). 1967; 20(6):344-8. View

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Omura S, Katagiri M, Awaya J, Furukawa T, Umezawa I, Oi N . Relationship between the structures of fatty acid amide derivatives and their antimicrobial activities. Antimicrob Agents Chemother. 1974; 6(2):207-15. PMC: 444628. DOI: 10.1128/AAC.6.2.207. View

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Ohno T, Awaya J, Omura S . Inhibition of sporulation by cerulenin and its reversion by exogenous fatty acids in Saccharomyces cerevisiae. Antimicrob Agents Chemother. 1976; 9(1):42-8. PMC: 429471. DOI: 10.1128/AAC.9.1.42. View

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Awaya J, Ohno T, Ohno H, Omura S . Substitution of cellular fatty acids in yeast cells by the antibiotic cerulenin and exogenous fatty acids. Biochim Biophys Acta. 1975; 409(3):267-73. DOI: 10.1016/0005-2760(75)90022-3. View

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Chopra I . Induction of tetracycline resistance in Staphylococcus aureus in the absence of lipid synthesis. J Gen Microbiol. 1975; 91(2):433-6. DOI: 10.1099/00221287-91-2-433. View