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Population Based Study of Fatigue and Psychological Distress

Overview
Journal BMJ
Specialty General Medicine
Date 1994 Mar 19
PMID 7908238
Citations 132
Authors
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Abstract

Objectives: To determine the prevalence of fatigue in the general population and the factors associated with fatigue.

Design: Postal survey.

Setting: Six general practices in southern England.

Subjects: 31,651 men and women aged 18-45 years registered with the practices.

Main Outcome Measures: Responses to the 12 item general health questionnaire and a fatigue questionnaire which included self reported measures of duration, severity, and causes of fatigue.

Results: 15,283 valid questionnaires were returned, giving a response rate of 48.3%, (64% after adjustment for inaccuracies in the practice registers). 2798 (18.3%) of respondents reported substantial fatigue lasting six months or longer. Fatigue and psychological morbidity were moderately correlated (r = 0.62). Women were more likely to complain of fatigue than men, even after adjustment for psychological distress. The commonest cited reasons for fatigue were psychosocial (40% of patients). Of 2798 patients with excessive tiredness, only 38 (1.4%) attributed this to the chronic fatigue syndrome.

Conclusion: Fatigue is distributed as a continuous variable in the community and is closely associated with psychological morbidity.

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References
1.
Payne-James J, Silk D . Clinical nutrition support. BMJ. 1990; 301(6742):1-2. PMC: 1663352. DOI: 10.1136/bmj.301.6742.1. View

2.
Wessely S, Powell R . Fatigue syndromes: a comparison of chronic "postviral" fatigue with neuromuscular and affective disorders. J Neurol Neurosurg Psychiatry. 1989; 52(8):940-8. PMC: 1031831. DOI: 10.1136/jnnp.52.8.940. View

3.
. Recent topics in cystic fibrosis. Symposium held by the Section of Pediatrics of the Royal Society of Medicine, 26 October 1990, London. J R Soc Med. 1991; 84 Suppl 18:1-39. PMC: 1293027. View

4.
Jones R, Lydeard S . Irritable bowel syndrome in the general population. BMJ. 1992; 304(6819):87-90. PMC: 1880997. DOI: 10.1136/bmj.304.6819.87. View

5.
David A . Postviral fatigue syndrome and psychiatry. Br Med Bull. 1991; 47(4):966-88. DOI: 10.1093/oxfordjournals.bmb.a072524. View