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Severe Osteomyelitis Due to the Zygomycete Apophysomyces Elegans

Overview
Journal J Clin Microbiol
Specialty Microbiology
Date 1994 Dec 1
PMID 7883908
Citations 17
Authors
J F Meis
B J Kullberg
M Pruszczynski
R P Veth
Affiliations
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Abstract

We describe a previously healthy 69-year-old man presenting with osteomyelitis of the humerus due to the zygomycete Apophysomyces elegans. The infection was acquired in Aruba, The Netherlands Antilles. The skin provided the most likely portal of entry, although there was no history of a traumatic inoculation. The patient had no history of diabetes, and no underlying immune defects were found. Despite treatment with 7.9 g of amphotericin B, an interthoracoscapular amputation proved necessary to curtail the rapid spread of the fungus in this immunocompetent host.

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