Blockade of LH-RH Induced Ovulation in Immature Rats by LH-RH Antiserum

Overview

Journal Can J Physiol Pharmacol

Specialties Pharmacology
Physiology

Date 1976 Jun 1

PMID 782672

Citations 1

Authors

M A Hirsch

M L GIVNER

Affiliations

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Abstract

An in vivo method for the determination of biological potency of luteinizing hormone-releasing hormone (LH-RH) antiserum is described. The procedure involves antiserum blockade of LH-RH induced ovulation in immature rats primed with pregnant mare's serum. A modified method for the induction of LH-RH antibodies in rabbits is also detailed.

Citing Articles

Immuno-histochemical localization of LH-RH during different phases of estrus cycle of rat, with reference to the preoptic and arcuate neurons, and the ependymal cells.

Naik D Cell Tissue Res. 1976; 173(2):143-66.

PMID: 791500 DOI: 10.1007/BF00221371.