Phase Behavior of Mixtures of Cholesterol and Saturated Phosphatidylglycerols

Overview

Journal Chem Phys Lipids

Specialty Biochemistry

Date 1995 May 22

PMID 7788803

Citations 14

Authors

N Borochov

E J Wachtel

D Bach

Affiliations

Soon will be listed here.

Abstract

The interaction of cholesterol with a series of saturated phosphatidylglycerols was investigated using differential scanning calorimetry and X-ray diffraction. We find that the miscibility of cholesterol in phosphatidylglycerol bilayers is lower than in the corresponding phosphatidylcholine bilayers and decreases with increasing acyl chain length of the phospholipid. The influence of the negative charge of the phosphatidylglycerol on cholesterol miscibility is discussed.

Citing Articles

Functional regulation of aquaporin dynamics by lipid bilayer composition.

Nguyen A, Weigle A, Shukla D Nat Commun. 2024; 15(1):1848.

PMID: 38418487 PMC: 10901782. DOI: 10.1038/s41467-024-46027-y.

Functional Regulation of Aquaporin Dynamics by Lipid Bilayer Composition.

Nguyen A, Weigle A, Shukla D bioRxiv. 2023; .

PMID: 37502896 PMC: 10370204. DOI: 10.1101/2023.07.20.549977.

Apolipoprotein E Binding Drives Structural and Compositional Rearrangement of mRNA-Containing Lipid Nanoparticles.

Sebastiani F, Yanez Arteta M, Lerche M, Porcar L, Lang C, Bragg R ACS Nano. 2021; 15(4):6709-6722.

PMID: 33754708 PMC: 8155318. DOI: 10.1021/acsnano.0c10064.

Cholesterol stimulates the cellular uptake of L-carnitine by the carnitine/organic cation transporter novel 2 (OCTN2).

Zhang L, Gui T, Console L, Scalise M, Indiveri C, Hausler S J Biol Chem. 2020; 296:100204.

PMID: 33334877 PMC: 7948396. DOI: 10.1074/jbc.RA120.015175.

Is phosphatidylglycerol essential for terrestrial life?.

Furse S J Chem Biol. 2017; 10(1):1-9.

PMID: 28101250 PMC: 5218921. DOI: 10.1007/s12154-016-0159-3.