Trigeminal Neuralgia in Multiple Sclerosis Relieved by a Prostaglandin E Analogue

Overview

Journal Neurology

Specialty Neurology

Date 1995 Jun 1

PMID 7783870

Citations 16

Authors

A T Reder

B G Arnason

Affiliations

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Abstract

Trigeminal neuralgia is an uncommon but troublesome symptom of multiple sclerosis that can be refractory to conventional treatments. Misoprostol, a long-acting prostaglandin E1 analogue, relieved pain in six of seven patients who had failed to respond to conventional pharmacologic therapy.

Citing Articles

Pain in Multiple Sclerosis: Understanding Pathophysiology, Diagnosis, and Management Through Clinical Vignettes.

Racke M, Frohman E, Frohman T Front Neurol. 2022; 12:799698.

PMID: 35095742 PMC: 8794582. DOI: 10.3389/fneur.2021.799698.

Trigeminal Neuralgia: Current Approaches and Emerging Interventions.

Xu R, Xie M, Jackson C J Pain Res. 2021; 14:3437-3463.

PMID: 34764686 PMC: 8572857. DOI: 10.2147/JPR.S331036.

Advances in the Understanding and Management of Chronic Pain in Multiple Sclerosis: a Comprehensive Review.

Urits I, Adamian L, Fiocchi J, Hoyt D, Ernst C, Kaye A Curr Pain Headache Rep. 2019; 23(8):59.

PMID: 31342191 DOI: 10.1007/s11916-019-0800-2.

Trigeminal neuralgia secondary to multiple sclerosis: from the clinical picture to the treatment options.

Stefano G, Maarbjerg S, Truini A J Headache Pain. 2019; 20(1):20.

PMID: 30782116 PMC: 6734488. DOI: 10.1186/s10194-019-0969-0.

Current and Innovative Pharmacological Options to Treat Typical and Atypical Trigeminal Neuralgia.

Di Stefano G, Truini A, Cruccu G Drugs. 2018; 78(14):1433-1442.

PMID: 30178160 PMC: 6182468. DOI: 10.1007/s40265-018-0964-9.