Demonstration of the Tuberoinfundibular Tract of the Cat: Fluorescence Histochemistry and Electron Microscopy

Overview

Journal Cell Tissue Res

Specialties Anatomy & Histology
Cell Biology

Date 1976 May 13

PMID 776408

Authors

Y Nojyo

Y Ibata

Y Sano

Affiliations

Soon will be listed here.

Abstract

The distribution of dopaminergic nerve cells in the cat hypothalamus, particularly in the arcuate and periventricular nuclei, and the projections of their axons were studied by fluorescence and electron microscopy after electrothermic coagulation. The majority of these perikarya were located in the arcuate nucleus and the periventricular nucleus dorsocaudal to the optic chiasma. Large lesions caused a wide and diffuse depletion of dopamine fluorescence within the external layer; small lesions caused ipsilateral partial depletion of the dopamine fluorescence. Electron microscopic observations in animals with a lesioned arcuate nucleus revealed that in the external layer degenerating nerve terminals are engulfed by glial processess. In some cases nerve fibers had entirely disappeared and a heavy reactive proliferation of glial processes was observed. Persistence of the form of the median eminence in spite of the extensive degeneration of its nervous elements is considered to depend upon this glial proliferation.

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