» Articles » PMID: 7763967

Dynamic Properties of Proteins from NMR Spectroscopy

Overview
Publisher Elsevier
Specialty Biotechnology
Date 1993 Aug 1
PMID 7763967
Citations 24
Authors
Affiliations
Soon will be listed here.
Abstract

Two-dimensional proton-detected heteronuclear nuclear magnetic resonance spectroscopy has been used to measure 13C and 15N spin-relaxation rate constants for several proteins. Generalized order parameters and effective internal correlation times have been calculated from the relaxation data to characterize intramolecular motions that are more rapid than overall rotational diffusion. These studies provide detailed descriptions of the magnitudes and timescales of fluctuations in protein molecules.

Citing Articles

Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons.

Alvarez Z, Ortega J, Sato K, Sasselli I, Kolberg-Edelbrock A, Qiu R Cell Stem Cell. 2023; 30(2):219-238.e14.

PMID: 36638801 PMC: 9898161. DOI: 10.1016/j.stem.2022.12.010.


Bioactive scaffolds with enhanced supramolecular motion promote recovery from spinal cord injury.

Alvarez Z, Kolberg-Edelbrock A, Sasselli I, Ortega J, Qiu R, Syrgiannis Z Science. 2021; 374(6569):848-856.

PMID: 34762454 PMC: 8723833. DOI: 10.1126/science.abh3602.


Local unfolding of the HSP27 monomer regulates chaperone activity.

Alderson T, Roche J, Gastall H, Dias D, Pritisanac I, Ying J Nat Commun. 2019; 10(1):1068.

PMID: 30842409 PMC: 6403371. DOI: 10.1038/s41467-019-08557-8.


Proline isomerization in the C-terminal region of HSP27.

Alderson T, Benesch J, Baldwin A Cell Stress Chaperones. 2017; 22(4):639-651.

PMID: 28547731 PMC: 5465039. DOI: 10.1007/s12192-017-0791-z.


NMR Analysis of Amide Hydrogen Exchange Rates in a Pentapeptide-Repeat Protein from A. thaliana.

Xu S, Ni S, Kennedy M Biophys J. 2017; 112(10):2075-2088.

PMID: 28538145 PMC: 5444007. DOI: 10.1016/j.bpj.2017.04.016.