» Articles » PMID: 7743589

Evolution of Operational Research Studies and Development of a National Control Strategy Against Intestinal Helminths in Pemba Island, 1988-92

Overview
Specialty Public Health
Date 1995 Jan 1
PMID 7743589
Citations 13
Authors
Affiliations
Soon will be listed here.
Abstract

Intestinal helminthic infections in Pemba Island, United Republic of Tanzania, have been perceived as a public health problem for many decades. School surveys in 1988 and 1992 and a community survey in 1991 were carried out to assess the distribution of prevalence and the intensity of these infections and to define the most effective strategy for control. The prevalence of helminthic infections exceeded 85% in all the surveys, and intensity was moderate. These studies identified the high-risk age groups, high transmission areas for different parasites, and the most cost-effective anthelminthic drug. This work is an example of how existing health systems and simple analytical tools may be used to generate useful data which, in turn, are used to define suitable intervention strategies. As a result, the Ministry of Health of Zanzibar has developed a national plan for the integrated control of intestinal helminths. This plan envisages periodic mass treatment of school-age children with mebendazole (500 mg, single dose, every four months) for the control of morbidity due to Ascaris, Trichuris, and hookworms.

Citing Articles

Neurocysticercosis: Current Perspectives on Diagnosis and Management.

Butala C, Brook T, Majekodunmi A, Welburn S Front Vet Sci. 2021; 8:615703.

PMID: 34041288 PMC: 8141574. DOI: 10.3389/fvets.2021.615703.


Efficacy and Safety of a Single Dose a Multiple Dose Regimen of Mebendazole against Hookworm Infections in Children: A Randomised, Double-blind Trial.

Palmeirim M, Ame S, Ali S, Hattendorf J, Keiser J EClinicalMedicine. 2019; 1:7-13.

PMID: 31193620 PMC: 6537524. DOI: 10.1016/j.eclinm.2018.06.004.


Preventive chemotherapy to control soil-transmitted helminthiasis averted more than 500 000 DALYs in 2015.

Montresor A, Trouleau W, Mupfasoni D, Bangert M, Joseph S, Mikhailov A Trans R Soc Trop Med Hyg. 2018; 111(10):457-463.

PMID: 29346640 PMC: 5808863. DOI: 10.1093/trstmh/trx082.


High occurrence of Blastocystis sp. subtypes 1-3 and Giardia intestinalis assemblage B among patients in Zanzibar, Tanzania.

Forsell J, Granlund M, Samuelsson L, Koskiniemi S, Edebro H, Evengard B Parasit Vectors. 2016; 9(1):370.

PMID: 27356981 PMC: 4928263. DOI: 10.1186/s13071-016-1637-8.


Is anthelmintic resistance a concern for the control of human soil-transmitted helminths?.

Vercruysse J, Albonico M, Behnke J, Kotze A, Prichard R, McCarthy J Int J Parasitol Drugs Drug Resist. 2014; 1(1):14-27.

PMID: 24533260 PMC: 3913213. DOI: 10.1016/j.ijpddr.2011.09.002.


References
1.
Albonico M, Renganathan E, Bosman A, Kisumku U, Alawi K, Savioli L . Efficacy of a single dose of mebendazole on prevalence and intensity of soil-transmitted nematodes in Zanzibar. Trop Geogr Med. 1994; 46(3):142-6. View

2.
Albonico M, DE CARNERI I, Di Matteo L, Ghiglietti R, Toscano P, Uledi M . Intestinal parasitic infections of urban and rural children on Pemba Island: implications for control. Ann Trop Med Parasitol. 1993; 87(6):579-83. DOI: 10.1080/00034983.1993.11812813. View

3.
Chunge R, KAMUNVI F, Kinoti S . Intestinal parasitoses in Kenya: a review of intestinal helminths in Kenya, 1900-1983. East Afr Med J. 1985; 62(8 Suppl):1-28. View

4.
Savioli L, Bundy D, Tomkins A . Intestinal parasitic infections: a soluble public health problem. Trans R Soc Trop Med Hyg. 1992; 86(4):353-4. DOI: 10.1016/0035-9203(92)90215-x. View

5.
Stephenson L, Latham M, Kinoti S, Kurz K, BRIGHAM H . Improvements in physical fitness of Kenyan schoolboys infected with hookworm, Trichuris trichiura and Ascaris lumbricoides following a single dose of albendazole. Trans R Soc Trop Med Hyg. 1990; 84(2):277-82. DOI: 10.1016/0035-9203(90)90286-n. View